Evidence map›Paper›PMID 26410599›Full record

ReviewTrends in biochemical sciences2015

Long Noncoding RNAs: A New Regulatory Code in Metabolic Control.

Xu-Yun Zhao, Jiandie D Lin

Abstract readReview
In one paragraph

Review in Trends in biochemical sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 1 synthesis or guideline pooled it, 220 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Metabolic memory: mechanisms and diseases.Signal transduction and targeted therapy · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Long Non-Coding RNAs: New Players in Plants.International journal of molecular sciences · 2022
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xu-Yun ZhaoLife Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Jiandie D LinLife Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: jdlin@umich.edu.
University of Michigan–Ann Arbor · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Metabolic crosstalk through brown fat-enriched secreted factorsR01DK102456 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jiandie D Lin · 2015 to 2026
$4.9M
PGC-1beta in the Regulation of Hepatic Lipid MetabolismR01DK077086 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIN, JIANDIE D · 2007 to 2015
$2.8M
Regulation of glycolytic muscle metabolismR01DK095151 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIN, JIANDIE D · 2012 to 2015
$1.4M
NIDDK NIH HHS DK077086NIDDK NIH HHS DK095151NIDDK NIH HHS P30 DK020572NIDDK NIH HHS R01 DK077086NIDDK NIH HHS R01 DK095151NIDDK NIH HHS R01 DK102456
6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) are emerging as an integral part of the regulatory information encoded in the genome. lncRNAs possess the unique capability to interact with nucleic acids and proteins, and exert discrete effects on numerous biological processes. Recent studies have delineated multiple lncRNA pathways that control metabolic tissue development and function. The expansion of the regulatory code that links nutrient and hormonal signals to tissue metabolism gives new insights into the genetic and pathogenic mechanisms underlying metabolic disease. This review discusses lncRNA biology with a focus on their role in the development, signaling, and function of key metabolic tissues.

Indexed as

AnimalsEnergy MetabolismHumansRNA, Long NoncodingRNA, Long Noncodingbrown fatenergy metabolismlncRNAmetabolic diseasesignalingtranscription

Identifiers

PMID26410599
PMCPMC4584418
OpenAlexW2117543913

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.