Evidence map›Paper›PMID 26410408›Full record

ReviewTrends in cell biology2015

Control of Chromatin Structure by Long Noncoding RNA.

Gudrun Böhmdorfer, Andrzej T Wierzbicki

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Trends in cell biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
173citing papers in PubMed, 3 pooled it
18.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

173 citing papers in PubMed, 3 syntheses or guidelines pooled it, 282 citations in OpenAlex.

  1. Pooled it
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  14. Unveiling the invisible genomic dynamics.Experimental & molecular medicine · 2025
    Review
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113 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gudrun BöhmdorferUniversity of Michigan, Department of Molecular, Cellular, and Developmental Biology, Ann Arbor, MI 48109, USA.
Andrzej T WierzbickiUniversity of Michigan, Department of Molecular, Cellular, and Developmental Biology, Ann Arbor, MI 48109, USA. Electronic address: wierzbic@umich.edu.
University of Michigan–Ann Arbor · US

Funding

Control of chromatin structure by long non-coding RNAR01GM108722 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WIERZBICKI, ANDRZEJ TOMASZ · 2014 to 2018
$1.5M
NIGMS NIH HHS R01 GM108722NIGMS NIH HHS R01GM108722
6 · The paper itself

Abstract

Long noncoding RNA (lncRNA) is a pivotal factor regulating various aspects of genome activity. Genome regulation via DNA methylation and post-translational histone modifications is a well-documented function of lncRNA in plants, fungi, and animals. Here, we summarize evidence showing that lncRNA also controls chromatin structure, including nucleosome positioning and chromosome looping. We focus on data from plant experimental systems, discussed in the context of other eukaryotes. We explain the mechanisms of lncRNA-controlled chromatin remodeling and the implications of the functional interplay between noncoding transcription and several different chromatin remodelers. We propose that the unique properties of RNA make it suitable for controlling chromatin modifications and structure.

Indexed as

ArabidopsisArabidopsis ProteinsChromatin Assembly and DisassemblyDNA-Directed RNA PolymerasesDNA MethylationHistonesNucleosomesProtein Processing, Post-TranslationalRNA, Long NoncodingArabidopsis ProteinsDNA-Directed RNA PolymerasesHistonesNucleosomesRNA, Long NoncodingRNA polymerase V, Arabidopsischromatin remodelingchromosome loopingnucleosomeRNA Polymerase V

Identifiers

PMID26410408
PMCPMC4584417
OpenAlexW2162105224

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.