ArticleInflammation research : official journal of the European Histamine Research Society ... [et al.]2015
Does occupational exposure to anesthetic gases lead to increase of pro-inflammatory cytokines?
Article in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Occupational Exposure to Inhalation Anesthetics in Operating Room and Adverse Health Outcomes: A Systematic Review.La Medicina del lavoro · 2026Pooled it
- Spontaneous abortion in women occupationally exposed to inhalational anesthetics: a critical systematic review.Environmental science and pollution research international · 2021Pooled it
- Anaesthesia Waste Gases and Bioethics: Balancing Patient Care, Environmental Responsibility, and Occupational Safety.Developing world bioethics · 2026Review
- Optimizing surgical site infection control systems: evaluating operating room ventilation system effectiveness in public hospitals.Scientific reports · 2026Article
- Spotlight on lung health in operating theatre staff.African journal of thoracic and critical care medicine · 2025Article
- Exposure to anesthetic gases in the operating rooms and assessment of non-carcinogenic risk among health care workers.Toxicology reports · 2023Article
- Establishing a health-based recommended occupational exposure limit for isoflurane using experimental animal data: a systematic review protocol.Systematic reviews · 2023Article
- Immunotoxicity induced by occupational inhalation exposure to waste anesthetic gases: a historical cohort study.Annals of medicine and surgery (2012) · 2023Article
- Effect of inhaled anaesthetics gases on cytokines and oxidative stress alterations for the staff health status in hospitals.International archives of occupational and environmental health · 2021Article
- Inhaled Anesthetics: Environmental Role, Occupational Risk, and Clinical Use.Journal of clinical medicine · 2021Review
- Pro-Con Debate: Nitrous Oxide for Labor Analgesia.BioMed research international · 2019Review
- Article
- [Occupational hazards, DNA damage, and oxidative stress on exposure to waste anesthetic gases].Brazilian journal of anesthesiology (Elsevier)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThere is great concern about the possible harmful effects of exposure to volatile anesthetics. The current study aimed at evaluating, for the first time, the effects of occupational exposure to anesthetic gases on physicians who work in operating rooms, by determining several inflammatory cytokines. MATERIALS AND
methodsPlasma inflammatory cytokines (IL-1β, -6, -8, -10, -12, TNF-α) were investigated in 30 individuals who were allocated into two groups of 15: the exposed group, consisting of operating room medical personnel exposed to a mixture of anesthetic gases for 3 years, and a control group composed of medical personnel not exposed to anesthetic gases. The concentrations of volatile anesthetics were measured in the operating room by means of an infrared portable analyzer RESULTS AND
conclusionsOur findings suggest an increase of the pro-inflammatory IL-8 (p<0.05) in medical personnel exposed to high concentrations of anesthetic gases, even for a relatively short period.
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Registered trials
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