ArticleThe Plant cell2015
Inference of Longevity-Related Genes from a Robust Coexpression Network of Seed Maturation Identifies Regulators Linking Seed Storability to Biotic Defense-Related Pathways.
Article in The Plant cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Seed Longevity in Legumes: Deeper Insights Into Mechanisms and Molecular Perspectives.Frontiers in plant science · 2022Pooled it
- SeedMatExplorer: the transcriptome atlas of Arabidopsis seed maturation.BMC plant biology · 2026Article
- Regulation of developmental transitions in plants: the role of VIVAPAROUS ABI3-LIKE (VAL) repressors.Journal of plant research · 2026Review
- Transcriptomic Profiling Reveals the Seed Aging Process inPlants (Basel, Switzerland) · 2026Article
- Molecular timekeepers: the curious alliance of redox, repair, and protective proteins in preserving seed longevity.Crop health · 2026Review
- Editorial: Molecular basis of seed germination and dormancy, volume II.Frontiers in plant science · 2026Article
- Environmental Factors, Developmental Genes and Oxidative Stress Determine Inter-Species Variability in Seed Longevity in Salicaceae.Plants (Basel, Switzerland) · 2025Article
- Unravelling the dynamics of seed-stored mRNAs during seed priming.The New phytologist · 2025Article
- Maternal environmental effects and climate-smart seeds: unlocking epigenetic inheritance for crop innovation in the seed industry.The Plant journal : for cell and molecular biology · 2025Article
- Deciphering Seed Deterioration: Molecular Insights and Priming Strategies for Revitalizing Aged Seeds.Plants (Basel, Switzerland) · 2025Review
- Unraveling the Mechanistic Basis for Control of Seed Longevity.Plants (Basel, Switzerland) · 2025Review
- 20 years of the Bio-Analytic Resource for Plant Biology.Nucleic acids research · 2025Article
- ABA-GA antagonism and modular gene networks cooperatively drive acquisition of desiccation tolerance in perilla seeds.Frontiers in plant science · 2025Article
- Dissecting the temporal genetic networks programming soybean embryo development from embryonic morphogenesis to post-germination.Plant cell reports · 2024Article
- Seed longevity and genome damage.Bioscience reports · 2024Review
- Article
- BASIC PENTACYSTEINE1 regulatesFrontiers in plant science · 2024Article
- Tropical peanut maturation scale for harvesting seeds with superior quality.Frontiers in plant science · 2024Article
- A Seed Storage Protocol to Determine Longevity.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Integrated multispectral imaging, germination phenotype, and transcriptomic analysis provide insights into seed vigor responsive mechanisms in quinoa under artificial accelerated aging.Frontiers in plant science · 2024Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seed longevity, the maintenance of viability during storage, is a crucial factor for preservation of genetic resources and ensuring proper seedling establishment and high crop yield. We used a systems biology approach to identify key genes regulating the acquisition of longevity during seed maturation of Medicago truncatula. Using 104 transcriptomes from seed developmental time courses obtained in five growth environments, we generated a robust, stable coexpression network (MatNet), thereby capturing the conserved backbone of maturation. Using a trait-based gene significance measure, a coexpression module related to the acquisition of longevity was inferred from MatNet. Comparative analysis of the maturation processes in M. truncatula and Arabidopsis thaliana seeds and mining Arabidopsis interaction databases revealed conserved connectivity for 87% of longevity module nodes between both species. Arabidopsis mutant screening for longevity and maturation phenotypes demonstrated high predictive power of the longevity cross-species network. Overrepresentation analysis of the network nodes indicated biological functions related to defense, light, and auxin. Characterization of defense-related wrky3 and nf-x1-like1 (nfxl1) transcription factor mutants demonstrated that these genes regulate some of the network nodes and exhibit impaired acquisition of longevity during maturation. These data suggest that seed longevity evolved by co-opting existing genetic pathways regulating the activation of defense against pathogens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.