Trial reportRestorative neurology and neuroscience2015
Do post-stroke patients benefit from robotic verticalization? A pilot-study focusing on a novel neurophysiological approach.
Trial report in Restorative neurology and neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Robot-assisted therapy following stroke: what effects on quality of life, cognitive and psychosocial outcomes? A systematic review.Journal of rehabilitation medicine · 2026Pooled it
- Effects of physical therapy modalities for motor function, functional recovery, and post-stroke complications in patients with severe stroke: a systematic review update.Systematic reviews · 2024Pooled it
- Systematic review of novel technology-based interventions for ischemic stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Pooled it
- Pooled it
- Effect of robot-assisted training on cognitive function in post-stroke patients: a meta-analysis.Frontiers in neurologyPooled it
- Safety and efficacy of add-on robotic therapy for early mobilization in intermediate neurocritical care: a pilot study.Journal of neuroengineering and rehabilitation · 2025Trial
- Effect of robotic tilt table verticalization on recovery in patients with disorders of consciousness: a randomized controlled trial.Journal of neurology · 2023Trial
- EMG Muscle Activation Pattern of Four Lower Extremity Muscles during Stair Climbing, Motor Imagery, and Robot-Assisted Stepping: A Cross-Sectional Study in Healthy Individuals.BioMed research international · 2019Trial
- Combined Robotic VErticalization and Lower Limb Mobilization in Patients with Severe Acquired Brain Injury: Protocol of a Multicenter Randomized Controlled Trial (VEM-sABI).Journal of clinical medicine · 2025Article
- Risk factors for post-stroke aspiration pneumonia in long-term hospitalized patients: a retrospective study.Journal of thoracic disease · 2025Article
- The Influence of Therapy Enriched with the ErigoBrain sciences · 2025Article
- Very early tilt-table verticalization unmasks impaired cerebral autoregulation within 24 h after endovascular thrombectomy: a transcranial Doppler study.Frontiers in neurology · 2025Article
- Cognitive Effects of Transcranial Direct Current Stimulation Plus Robotic Verticalization in Minimally Conscious State.Biomedicines · 2024Article
- Effects of Rehabilitation Robot Training on Physical Function, Functional Recovery, and Daily Living Activities in Patients with Sub-Acute Stroke.Medicina (Kaunas, Lithuania) · 2024Article
- Improving Neuroplasticity through Robotic Verticalization Training in Patients with Minimally Conscious State: A Retrospective Study.Brain sciences · 2024Article
- Barriers and facilitators in the implementation of mobilization robots in hospitals from the perspective of clinical experts and developers.BMC nursing · 2023Article
- Robot-assisted early mobilization of intensive care patients: a feasibility study protocol.Pilot and feasibility studies · 2022Article
- [Early mobilization in the intensive care unit-Are robot-assisted systems the future?]Die Anaesthesiologie · 2022Review
- Robotic Verticalization plus Music Therapy in Chronic Disorders of Consciousness: Promising Results from a Pilot Study.Brain sciences · 2022Article
- A Literature Review of High-Tech Physiotherapy Interventions in the Elderly with Neurological Disorders.International journal of environmental research and public health · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTilt-table equipped with the dynamic foot-support (ERIGO) and the functional electric stimulation could be a safe and suitable device for stabilization of vital signs, increasing patient's motivation for further recovery, decreasing the duration of hospitalization, and accelerating the adaptation to vertical posture in bedridden patients with brain-injury. Moreover, it is conceivable that verticalization may improve cognitive functions, and induce plastic changes at sensory motor and vestibular system level that may in turn facilitate motor functional recovery.
objectiveTo test the safety and effectiveness of ERIGO treatment on motor and cognitive functions, cortical plasticity within vestibular and sensory-motor systems in a bedridden post-stroke sample.
methods20 patients were randomly divided in two groups that performed ERIGO training (30 sessions) (G1) or physiotherapist-assisted verticalization training (same duration) (G2), beyond conventional neurorehabilitation treatment. Motor and cognitive functions as well as sensory-motor and vestibular system plasticity were investigated either before (T0) or after (T1) the rehabilitative protocols.
resultsBoth the verticalization treatments were well-tolerated. Notably, the G1 patients had a significant improvement in cognitive function (p = 0.03), global motor function (p = 0.006), sensory-motor (p < 0.001) and vestibular system plasticity (p = 0.02) as compared to G2.
conclusionsERIGO training could be a valuable tool for the adaptation to the vertical position with a better global function improvement, as also suggested by the sensory-motor and vestibular system plasticity induction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.