ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015
A Blueprint to Address Research Gaps in the Development of Biomarkers for Pediatric Tuberculosis.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Pooled it
- Pooled it
- Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children.Scientific reports · 2017Trial
- Applications and prospects of artificial intelligence in the auxiliary diagnosis of pediatric pulmonary tuberculosis.Frontiers in microbiology · 2025Review
- Feasibility and utility of a combined nasogastric-tube-and-string-test device for bacteriologic confirmation of pulmonary tuberculosis in young children.Diagnostic microbiology and infectious disease · 2024Article
- Host-Based Biomarkers in Saliva for the Diagnosis of Pulmonary Tuberculosis in Children: A Mini-Review.Frontiers in pediatrics · 2021Review
- Integration of metabolomics and transcriptomics reveals novel biomarkers in the blood for tuberculosis diagnosis in children.Scientific reports · 2020Observational
- Diagnostic performance of culture filtered protein 10-specific perforin in pediatric patients with active tuberculosis.Journal of clinical laboratory analysis · 2020Article
- A three-marker protein biosignature distinguishes tuberculosis from other respiratory diseases in Gambian children.EBioMedicine · 2020Article
- Antibody-Secreting Cells To Diagnose Mycobacterium tuberculosis Infection in Children in Pakistan.mSphere · 2020Article
- Microbiological diagnosis of pulmonary tuberculosis in children by oral swab polymerase chain reaction.Scientific reports · 2019Article
- An Observational Case-Control Study to Determine Human Immunodeficiency Virus and Host Factor Influence on Biomarker Distribution and Serodiagnostic Potential in Adult Pulmonary Tuberculosis.Tropical medicine and infectious disease · 2019Article
- A Model Based on the Combination of IFN-γ, IP-10, Ferritin and 25-Hydroxyvitamin D for Discriminating Latent From Active Tuberculosis in Children.Frontiers in microbiology · 2019Article
- Tuberculosis in Children.Pediatric clinics of North America · 2017Review
- Diagnosis of pulmonary tuberculosis and assessment of treatment response through analyses of volatile compound patterns in exhaled breath samples.The Journal of infection · 2017Article
- Assessment of treatment response in tuberculosis.Expert review of respiratory medicine · 2016Review
Corrections and comments
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Authors and funding
17 authors at 13 institutions in 6 countries.
Funding
Abstract
Childhood tuberculosis contributes significantly to the global tuberculosis disease burden but remains challenging to diagnose due to inadequate methods of pathogen detection in paucibacillary pediatric samples and lack of a child-specific host biomarker to identify disease. Accurately diagnosing tuberculosis in children is required to improve case detection, surveillance, healthcare delivery, and effective advocacy. In May 2014, the National Institutes of Health convened a workshop including researchers in the field to delineate priorities to address this research gap. This blueprint describes the consensus from the workshop, identifies critical research steps to advance this field, and aims to catalyze efforts toward harmonization and collaboration in this area.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.