Evidence map›Paper›PMID 26409272›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015

Implementation of HIV and Tuberculosis Diagnostics: The Importance of Context.

Joyelle K Dominique, Alberto A Ortiz-Osorno, Joseph Fitzgibbon, Devasena Gnanashanmugam, Christopher Gilpin, Timothy Tucker, Sheila Peel, Trevor Peter, Peter Kim, Steven Smith

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Nucleic Acid Point-of-Care Testing to Improve Diagnostic Preparedness.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  4. Article
  5. Article
  6. Review
  7. What tuberculosis can teach us about combating multidrug-resistant Gram negative bacilli.Journal of clinical tuberculosis and other mycobacterial diseases · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joyelle K DominiqueOffice of Global Research, Office of Science Management and Operations, Office of the Director.
Alberto A Ortiz-OsornoClinical Research Implementation Subject Matter Expert, Henry M. Jackson Foundation, Division of AIDS Therapeutic Research Program, Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, US Department of Health and Human Services, Rockville, Maryland.
Joseph FitzgibbonTherapeutic Research Program, Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, US Department of Health and Human Services, Rockville, Maryland.
Devasena GnanashanmugamAdolescent and Pediatric Research Branch, Prevention Sciences Program, Division of AIDS.
Christopher GilpinWorld Health Organization, Geneva, Switzerland.
Timothy TuckerStrategic Evaluation, Advisory and Development Consulting, Cape Town, South Africa.
Sheila PeelDiagnostics and Laboratory Monitoring, US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Trevor PeterDiagnostics, Clinton Health Access Initiative, Gaborone, Botswana.
Peter KimAdolescent and Pediatric Research Branch, Prevention Sciences Program, Division of AIDS.
Steven SmithOffice of Global Affairs, Office of the Secretary, US Department of Health and Human Services, Pretoria, South Africa.

Funding

NIAID NIH HHS HHSN272200800014CWorld Health Organization 001
6 · The paper itself

Abstract

backgroundNovel diagnostics have been widely applied across human immunodeficiency virus (HIV) and tuberculosis prevention and treatment programs. To achieve the greatest impact, HIV and tuberculosis diagnostic programs must carefully plan and implement within the context of a specific healthcare system and the laboratory capacity.

methodsA workshop was convened in Cape Town in September 2014. Participants included experts from laboratory and clinical practices, officials from ministries of health, and representatives from industry.

resultsThe article summarizes best practices, challenges, and lessons learned from implementation experiences across sub-Saharan Africa for (1) building laboratory programs within the context of a healthcare system; (2) utilizing experience of clinicians and healthcare partners in planning and implementing the right diagnostic; and (3) evaluating the effects of new diagnostics on the healthcare system and on patient health outcomes.

conclusionsThe successful implementation of HIV and tuberculosis diagnostics in resource-limited settings relies on careful consideration of each specific context.

Indexed as

Health ResourcesBenchmarkingDelivery of Health CareHIV InfectionsHumansLaboratoriesPoint-of-Care SystemsSouth AfricaTuberculosisdiagnosticsdiagnostics’ implementationHIVpoint-of-caretuberculosis

Identifiers

PMID26409272
PMCPMC4583566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.