Evidence map›Paper›PMID 26409192›Full record

ArticleNanomedicine : nanotechnology, biology, and medicine2016

Platelet mimicry: The emperor's new clothes?

Seyed Moein Moghimi, Alan Christy Hunter, Dan Peer

Abstract readLetterComment
PubMed Publisher
In one paragraph

Article in Nanomedicine : nanotechnology, biology, and medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Nanometer- and angstrom-scale characteristics that modulate complement responses to nanoparticles.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Bio-inspired nanomedicine strategies for artificial blood components.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Seyed Moein MoghimiCentre for Pharmaceutical Nanotechnology and Nanotoxicology and Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark. Electronic address: moein.moghimi@gmail.com.
Alan Christy HunterManchester Pharmacy School, University of Manchester, Manchester, UK. Electronic address: christy.hunter@manchester.ac.uk.
Dan PeerLaboratory of Nanomedicine, Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel; Department of Materials Science and Engineering, The Iby and Aladar Fleischman Faculty of Engineering, Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, Israel. Electronic address: peer@tauex.tau.ac.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we critically examine whether coating of nanoparticles with platelet membranes can truly disguise them against recognition by elements of the innate immune system. We further assess whether the "cloaking technology" can sufficiently equip nanoparticles with platelet-mimicking functionalities to include in vivo targeting of damaged blood vessels and binding to platelet-adhering opportunistic pathogens. We present views for improved, and pharmaceutically viable nanoparticle design strategies.

Indexed as

Platelet AdhesivenessAnimalsAnti-Bacterial AgentsBlood PlateletsCell MembraneDrug Delivery SystemsHumansMaleNanoparticlesAnti-Bacterial AgentsComplementInnate immunityMacrophageNanoparticlesPlatelets

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.