Evidence map›Paper›PMID 26409031›Full record

ReviewNeurobiology of disease2016

Perinatal brain damage: The term infant.

Henrik Hagberg, A David Edwards, Floris Groenendaal

Registry-linked trialAbstract readReview
In one paragraph

Review in Neurobiology of disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07024771 (A Study On Association Between Neurological Pupil Index and Clinical Severity of Hypoxic Ischemic Encephalopathy In Neonates Admitted To Neonatal Neurocritical Care Unit), which is not on this map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07024771 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Study On Association Between Neurological Pupil Index and Clinical Severity of Hypoxic Ischemic Encephalopathy In Neonates Admitted To Neonatal Neurocritical Care Unit

TypeobservationalSponsorUniversity of CalgaryRan2025 to 2026Enrolled25ConditionsHypoxic Ischemic Encephalopathy (HIE)ArmsAutomated Pupillometer
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Observational
  5. Inflammatory mechanisms contribute to long-term cognitive deficits induced by perinatal asphyxia via interleukin-1.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Henrik HagbergCentre for the Developing Brain, Department of Perinatal Imaging and Health, Division of Imaging and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, SE1 7EH, United Kingdom; Perinatal Center, Dept of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden.
A David EdwardsCentre for the Developing Brain, Department of Perinatal Imaging and Health, Division of Imaging and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, SE1 7EH, United Kingdom.
Floris GroenendaalDepartment of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

Funding

Medical Research Council G0802853Wellcome TrustWellcome Trust WT094823 HH
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBrainBrain InjuriesHumansInfant, NewbornBrain injuryDiagnosisHypothermiaHypoxia–ischaemiaNeonatal encephalopathyNeuroprotectionPerinatal

Identifiers

PMID26409031
PMCPMC4915441

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.