ArticleNeuroImage2016
Automated cerebellar lobule segmentation with application to cerebellar structural analysis in cerebellar disease.
Article in NeuroImage, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Automated Segmentation of Tissues Using CT and MRI: A Systematic Review.Academic radiology · 2019Pooled it
- Neuroimmune mechanisms of the cerebellum-brainstem network in autoimmune encephalitis and related neuroimmune disorders: antibody targets, selective vulnerability, and translational opportunities.Frontiers in immunology · 2026Review
- Convolutional Neural Network for Fully Automated Cerebellar Volumetry in Children in Comparison to Manual Segmentation and Developmental Trajectory of Cerebellar Volumes.Cerebellum (London, England) · 2024Article
- Three-Dimensional Digital Reconstruction of the Cerebellar Cortex: Lobule Thickness, Surface Area Measurements, and Layer Architecture.Cerebellum (London, England) · 2023Article
- CerebNet: A fast and reliable deep-learning pipeline for detailed cerebellum sub-segmentation.NeuroImage · 2022Article
- Effects of combat sports on cerebellar function in adolescents: a resting-state fMRI study.The British journal of radiology · 2022Article
- Quantitative susceptibility mapping reveals alterations of dentate nuclei in common types of degenerative cerebellar ataxias.Brain communications · 2022Article
- Unique Morphometric Features of the Cerebellum and Cerebellocerebral Structural Correlation Between Autism Spectrum Disorder and Schizophrenia.Biological psychiatry global open science · 2021Article
- Anatomical texture patterns identify cerebellar distinctions between essential tremor and Parkinson's disease.Human brain mapping · 2021Article
- Automatic cerebellum anatomical parcellation using U-Net with locally constrained optimization.NeuroImage · 2020Article
- Graded Cerebellar Lobular Volume Deficits in Adolescents and Young Adults with Fetal Alcohol Spectrum Disorders (FASD).Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Evaluating White Matter Lesion Segmentations with Refined Sørensen-Dice Analysis.Scientific reports · 2020Article
- Accelerated aging and motor control deficits are related to regional deformation of central cerebellar white matter in alcohol use disorder.Addiction biology · 2020Article
- Current concepts of cross-sectional and functional anatomy of the cerebellum: a pictorial review and atlas.The British journal of radiology · 2020Article
- Hierarchical Parcellation of the Cerebellum.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2019Article
- Cerebellum Parcellation with Convolutional Neural Networks.Proceedings of SPIE--the International Society for Optical Engineering · 2019Article
- Convergence of three parcellation approaches demonstrating cerebellar lobule volume deficits in Alcohol Use Disorder.NeuroImage. Clinical · 2019Article
- Comparing fully automated state-of-the-art cerebellum parcellation from magnetic resonance images.NeuroImage · 2018Article
- Structural cerebellar correlates of cognitive functions in spinocerebellar ataxia type 2.Journal of neurology · 2018Article
- Structural cerebellar correlates of cognitive and motor dysfunctions in cerebellar degeneration.Brain : a journal of neurology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
The cerebellum plays an important role in both motor control and cognitive function. Cerebellar function is topographically organized and diseases that affect specific parts of the cerebellum are associated with specific patterns of symptoms. Accordingly, delineation and quantification of cerebellar sub-regions from magnetic resonance images are important in the study of cerebellar atrophy and associated functional losses. This paper describes an automated cerebellar lobule segmentation method based on a graph cut segmentation framework. Results from multi-atlas labeling and tissue classification contribute to the region terms in the graph cut energy function and boundary classification contributes to the boundary term in the energy function. A cerebellar parcellation is achieved by minimizing the energy function using the α-expansion technique. The proposed method was evaluated using a leave-one-out cross-validation on 15 subjects including both healthy controls and patients with cerebellar diseases. Based on reported Dice coefficients, the proposed method outperforms two state-of-the-art methods. The proposed method was then applied to 77 subjects to study the region-specific cerebellar structural differences in three spinocerebellar ataxia (SCA) genetic subtypes. Quantitative analysis of the lobule volumes shows distinct patterns of volume changes associated with different SCA subtypes consistent with known patterns of atrophy in these genetic subtypes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.