Evidence map›Paper›PMID 26408508›Full record

ReviewCancer biology & therapy2015

Non-functional parathyroid carcinoma: a case report and review of the literature.

Liang Wang, Dali Han, Wanjun Chen, Shuguang Zhang, Zhiqi Wang, Ke Li, Yongsheng Gao, Shujuan Zou, Aiju Yang

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in Cancer biology & therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Parathyroid carcinoma: epidemiology and genetics.Endocrine oncology (Bristol, England) · 2026
    Review
  5. Diagnosing the silent: the molecular landscape of non-functional parathyroid carcinoma.Virchows Archiv : an international journal of pathology · 2025
    Review
  6. Case presentation of the smallest non-functional parathyroid carcinoma and review of the literature.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Review
  7. Article
  8. Review
  9. Parathyroid carcinoma detected within the thyroid.Nagoya journal of medical science · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Liang Wanga Department of Head and Neck Surgery ; Shandong Cancer Hospital & Institute ; Jinan , China.
Dali Hanc Department of Radiation Oncology ; Shandong Cancer Hospital & Institute ; Jinan , China.
Wanjun Chena Department of Head and Neck Surgery ; Shandong Cancer Hospital & Institute ; Jinan , China.
Shuguang Zhanga Department of Head and Neck Surgery ; Shandong Cancer Hospital & Institute ; Jinan , China.
Zhiqi Wanga Department of Head and Neck Surgery ; Shandong Cancer Hospital & Institute ; Jinan , China.
Ke Lia Department of Head and Neck Surgery ; Shandong Cancer Hospital & Institute ; Jinan , China.
Yongsheng Gaod Department of Pathology ; Shandong Cancer Hospital & Institute ; Jinan , China.
Shujuan Zoua Department of Head and Neck Surgery ; Shandong Cancer Hospital & Institute ; Jinan , China.
Aiju Yanga Department of Head and Neck Surgery ; Shandong Cancer Hospital & Institute ; Jinan , China.
Shandong First Medical University · CNShandong Tumor Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-functional parathyroid carcinoma is an exceedingly rare disease with 31 reported cases since 1909. Because of the scarce number of cases of non-functional parathyroid carcinoma, there are no evidence-based recommendations for its optimal treatment. Surgery, including en bloc resection of the carcinoma, ipsilateral thyroid lobe and isthmus together with a neck dissection only in case of lymph node involvement, is the main treatment for non-functioning parathyroid carcinoma. The patient usually has a poorer prognosis because of detection at advanced stages, the relative ineffectiveness of adjuvant treatment modalities and the lack of adequate parameters for clinical follow-up. In this report, we present a case of non-functional parathyroid carcinoma at our institution, and we review the previous literature to discuss the latest advances in the diagnosis and treatment of this rare disease.

Indexed as

AdenomaFemaleHumansMiddle AgedNeoplasm Recurrence, LocalParathyroid GlandsParathyroid NeoplasmsUltrasonographycarcinomanon-functionalparathyroidsurgery

Identifiers

PMID26408508
PMCPMC4846094
OpenAlexW2142165223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.