ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2016
The effect of preventive oral care on treatment outcomes of a cohort of oral cancer patients.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Systematic review of basic oral care for the management of oral mucositis in cancer patients and clinical practice guidelines.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Pooled it
- Impact of an oral care intervention protocol on oral health outcomes in head and neck cancer patients undergoing radiation or chemoradiation therapy.BMC oral health · 2025Trial
- Cost-effectiveness randomized clinical trial on the effect of photobiomodulation therapy for prevention of radiotherapy-induced severe oral mucositis in a Brazilian cancer hospital setting.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Trial
- Clinical profile and pattern of second primary tumors in HPV-positive and HPV-negative oropharyngeal cancer.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2026Article
- Bridging the gap - Establishing a dental-oncology service in a cancer centre.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Significance of Multidisciplinary Teams for Patients with Oral and Maxillofacial Surgical Diseases: An Observational Retrospective Study in a General Hospital in China.Journal of multidisciplinary healthcare · 2024Article
- Oral Health Management and Rehabilitation for Patients with Oral Cancer: A Narrative Review.Healthcare (Basel, Switzerland) · 2022Review
- Including dental professionals in the multidisciplinary treatment team of head and neck cancer patients improves long-term oral health status.Clinical oral investigations · 2022Article
- MicroRNA-487a-3p inhibits the growth and invasiveness of oral squamous cell carcinoma by targeting PPM1A.Bioengineered · 2021Article
- Predictive factors for dental inflammation with exacerbation during cancer therapy with FDG-PET/CT imaging.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- A prospective study on oral adverse effects in head and neck cancer patients submitted to a preventive oral care protocol.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Observational
- Adherence to dental treatment reduces oral complications related to cancer treatment in pediatric and adolescent patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- A novel prognostic index for oral squamous cell carcinoma patients with surgically treated.Oncotarget · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to assess patient adherence to an oral preventive measures (OPM) protocol and its impact on cancer treatment outcomes.
methodsA retrospective cohort of oral cancer of 133 patients submitted to radiotherapy (RT) was selected, excluding those with metastasis. Patients were grouped according to their local tumor response after finishing RT (favorable or unfavorable) and adherence to an OPM (none, ≤6 months, and >6 months). OPM included education and counseling about adverse effects, elimination of infection foci, restorative procedures, fluoride therapy, oral rehydration, and maintenance and supervision of oral hygiene throughout treatment. Clinical and pathological characteristics were recorded, and patient outcomes (frequency of adverse effects, RT interruption, and overall survival) were analyzed.
resultsPatients with higher adherence to the OPM had greater occurrence of RT interruption as a consequence of symptoms (p = 0.01); however, these patients were more likely to complete the established RT protocol (p = 0.02). Overall survival (p = 0.01) was higher in the group with higher adherence.
conclusionsThis study suggests that the implementation of oral preventive measures may contribute to improving the prognosis of squamous cell carcinoma (SCC) treatment by reducing the negative impact of oral complications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.