Trial reportBMC complementary and alternative medicine2015
Anti-obesity effects of Yerba Mate (Ilex Paraguariensis): a randomized, double-blind, placebo-controlled clinical trial.
Trial report in BMC complementary and alternative medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01778257 (Mate Extract Supplementation Reduces Body and Abdominal Fat in Obese Korean Subjects), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mate Extract Supplementation Reduces Body and Abdominal Fat in Obese Korean Subjects
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.
- Yerba Maté and its impact on glycemic control and metabolic health: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Yerba Mate (Ilex paraguariensis St. Hill.) Tea May Have Cardiometabolic Beneficial Effects in Healthy and At-Risk Subjects: A Randomized, Controlled, Blind, Crossover Trial in Nonhabitual Consumers.Molecular nutrition & food research · 2025Trial
- Antiobesity and Hypolipidemic Potential ofNutrients · 2024Trial
- Effect of StandardizedNutrients · 2022Trial
- A Randomized Crossover Intervention Study on the Effect a Standardized Maté Extract (Nutrients · 2020Trial
- Trial
- Effect of yerba mate and green tea on paraoxonase and leptin levels in patients affected by overweight or obesity and dyslipidemia: a randomized clinical trial.Nutrition journal · 2019Trial
- Yerba Maté (Ilex paraguariensis) Metabolic, Satiety, and Mood State Effects at Rest and during Prolonged Exercise.Nutrients · 2017Trial
- Cardiometabolic Effects of Ilex paraguariensis (Yerba Mate): A Narrative Review of Evidence and Research Gaps.Cureus · 2026Review
- Anti-Obesity Effects of Pear Extract (International journal of stem cells · 2026Article
- Acute Effects of Commercial Yerba Mate Products on Cardiometabolic Responses during Submaximal Cycling: Brewed to Perform?Current developments in nutrition · 2026Article
- Article
- Bioactive Compounds of Ilex paraguariensis: A Critical Update on Extraction, Gastrointestinal Stability, and Technological Applications.Journal of food science · 2025Review
- Herbal Medicines for Weight Loss and Lipid Profile Improvement: A Scoping Review of Therapeutic Effects and Safety.Phytotherapy research : PTR · 2025Article
- The Incretin Effect of Yerba Maté (Nutrients · 2025Article
- Methodological insights into intervention and outcomes in randomised controlled trials of herbal medicine for obesity: a scoping review.Therapeutic advances in chronic disease · 2025Article
- Article
- Medicinal Plant Extracts against Cardiometabolic Risk Factors Associated with Obesity: Molecular Mechanisms and Therapeutic Targets.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Effects ofHeliyon · 2024Article
- Yerba Maté (Nutrients · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity is a major health problem. A food field research that has recently aroused considerable interest is the potential of natural products to counteract obesity. Yerba Mate may be helpful in reducing body weight and fat. The aim of this study was to investigate the efficacy and safety of Yerba Mate supplementation in Korean subjects with obesity.
methodsA randomized, double-blind, placebo-controlled trial was conducted. Subjects with obesity (body mass index (BMI) ≥ 25 but < 35 kg/m(2) and waist-hip ratio (WHR) ≥ 0.90 for men and ≥ 0.85 for women) were given oral supplements of Yerba Mate capsules (n = 15) or placebos (n = 15) for 12 weeks. Subjects take three capsules per each meal, total three times in a day (3 g/day). Measured outcomes were efficacy (abdominal fat distribution, anthropometric parameters and blood lipid profiles) and safety (adverse events, laboratory test results and vital signs).
resultsDuring 12 weeks of Yerba Mate supplementation, decreases in body fat mass (P = 0.036) and percent body fat (P = 0.030) compared to the placebo group were statistically significant. WHR was significantly decreased (P = 0.004) in the Yerba Mate group compared to the placebo group. No clinically significant changes in any safety parameters were observed.
conclusionsYerba Mate supplementation decreased body fat mass, percent body fat and WHR. Yerba Mate was a potent anti-obesity reagent that did not produce significant adverse effects. These results suggested that Yerba Mate supplementation may be effective for treating obese individuals.
trial registrationClinicalTrials.gov: (NCT01778257).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.