ArticleBMC genomics2015
Glutamine rapidly induces the expression of key transcription factor genes involved in nitrogen and stress responses in rice roots.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed, 147 citations in OpenAlex.
- Functional Characterization of the Oat (International journal of molecular sciences · 2026Article
- Asparagine Synthetase 1 regulates rice seminal root elongation via jasmonic acid metabolism.Plant cell reports · 2026Article
- A wheat MYB transcription factor activates defense by repressing TaSIZ1 in response to branched-chain amino acid accumulation.The Plant cell · 2026Article
- Progress and new questions in understanding the mechanisms controlling plant nitrogen responses.Plant biotechnology (Tokyo, Japan) · 2026Article
- Enhancing cereal productivity via nitrogen use efficiency: from conventional breeding to modern genomics.Frontiers in genetics · 2026Review
- Glutamine alleviates the toxicity of externally applied amino acids in Arabidopsis.Frontiers in plant science · 2026Article
- Metabolite profiling to evaluate metabolic changes in drought-tolerant transformant (Agb0103) under salt stress.GM crops & food · 2025Article
- Biological agents and plant growth regulator promote rice growth and regenerative capacity.BMC plant biology · 2025Article
- Initiation of Direct Shoot Organogenesis in Coconut Using Immature Inflorescence.Plants (Basel, Switzerland) · 2025Article
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- The amino acid permeaseHorticulture research · 2025Article
- Root exudates in controlled environment agriculture: composition, function, and future directions.Frontiers in plant science · 2025Review
- Growth characteristics of HCT116 xenografts lacking asparagine synthetase vary according to sex.Human genomics · 2024Article
- A Study on the Effect of Various Media and the Supplementation of Organic Compounds on the Enhanced Production of Astaxanthin fromMicroorganisms · 2024Article
- Glutamine as sole nitrogen source prevents induction of nitrate transporter geneFrontiers in plant science · 2024Article
- Mechanisms of metabolic adaptation in the duckweed Lemna gibba: an integrated metabolic, transcriptomic and flux analysis.BMC plant biology · 2023Article
- Genomic insights into Bacillus subtilis MBB3B9 mediated aluminium stress mitigation for enhanced rice growth.Scientific reports · 2023Article
- Amino Acid Catabolism: An Overlooked Area of Metabolism.Nutrients · 2023Review
- Moonlight Is Perceived as a Signal Promoting Genome Reorganization, Changes in Protein and Metabolite Profiles and Plant Growth.Plants (Basel, Switzerland) · 2023Article
- Hydropriming and Nutripriming of Bread Wheat Seeds Improved the Flour's Nutritional Value of the First Unprimed Offspring.Plants (Basel, Switzerland) · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlutamine is a major amino donor for the synthesis of amino acids, nucleotides, and other nitrogen-containing compounds in all organisms. In addition to its role in nutrition and metabolism, glutamine can also function as a signaling molecule in bacteria, yeast, and humans. By contrast, the functions of glutamine in nutrition and as a signaling molecule remain unclear in plants.
resultsWe demonstrated that glutamine could effectively support the growth of rice seedlings. In glutamine-treated rice roots, the glutamine contents increased dramatically, whereas levels of glutamate remained relatively constant. Transcriptome analysis of rice roots revealed that glutamine induced the expression of at least 35 genes involved in metabolism, transport, signal transduction, and stress responses within 30 min. Interestingly, 10 of the 35 early glutamine responsive genes encode putative transcription factors, including two LBD37-like genes that are involved in the regulation of nitrogen metabolism. Glutamine also rapidly induced the expression of the DREB1A, IRO2, and NAC5 transcription factor genes, which are involved in the regulation of stress responses.
conclusionsIn addition to its role as a metabolic fuel, glutamine may also function as a signaling molecule to regulate gene expression in plants. The rapid induction of transcription factor genes suggests that glutamine may efficiently amplify its signal and interact with the other signal transduction pathways to regulate plant growth and stress responses. Thus, glutamine is a functional amino acid that plays important roles in plant nutrition and signal transduction.
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