Evidence map›Paper›PMID 26407817›Full record

ArticleJournal of clinical periodontology2015

Site-specific treatment outcome in smokers following non-surgical and surgical periodontal therapy.

Dagmar F Bunaes, Stein Atle Lie, Morten Enersen, Anne Nordrehaug Aastrøm, Kamal Mustafa, Knut N Leknes

3 registry-linked trialsAbstract read
In one paragraph

Article in Journal of clinical periodontology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04493398 nacompletednot on this map

Erythritol Air-polishing Versus Curette/Ultrasonic Debridement of Mandibular Furcation Lesions in Supportive Periodontal Therapy A 12-Month Randomized Controlled Trial

TypeinterventionalSponsorUniversity of BergenRan2015 to 2018Enrolled20ConditionsPeriodontitis, Adult PeriodontitisArmsGracey curette., Ultrasonic scaler., Erythritol air-polishing.
NCT04952428 completednot on this mapstarted 2021, after this paper: background citation

Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study

TypeobservationalSponsorUniversitat Internacional de CatalunyaRan2021 to 2021Enrolled117ConditionsPeri-Implantitis, Peri-implant Mucositis, Bone Loss, AlveolarArmsRe-examination visit ("today visit")
NCT05120206 nacompletednot on this map

Outcomes of Periodontal Therapy in Smokers and Non-smokers With Chronic Periodontitis

TypeinterventionalSponsorUniversity of BergenRan2012 to 2015Enrolled80ConditionsPeriodontitis, Cigarette SmokingArmsNon-surgical periodontal therapy: motivation and instruction in oral hygiene, debridement using handinstrumentation (Hu-Firedy,Chicago, IL, USA, and American Eagle Instruments,Missoula, MT,USA).
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Influence of Smoking on Periodontal and Implant Therapy: A Narrative Review.International journal of environmental research and public health · 2023
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Smoking and periodontal microorganisms.The Japanese dental science review · 2019
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dagmar F BunaesFaculty of Medicine and Dentistry, Department of Clinical Dentistry, University of Bergen, Bergen, Norway.ORCID http://orcid.org/0000-0002-8592-7467
Stein Atle LieFaculty of Medicine and Dentistry, Department of Clinical Dentistry, University of Bergen, Bergen, Norway.
Morten EnersenFaculty of Dentistry, Institute of Oral Biology, University of Oslo, Oslo, Norway.
Anne Nordrehaug AastrømFaculty of Medicine and Dentistry, Department of Clinical Dentistry, University of Bergen, Bergen, Norway.
Kamal MustafaFaculty of Medicine and Dentistry, Department of Clinical Dentistry, University of Bergen, Bergen, Norway.
Knut N LeknesFaculty of Medicine and Dentistry, Department of Clinical Dentistry, University of Bergen, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the effect of smoking at patient, tooth, and site level following non-surgical and surgical periodontal therapy. MATERIAL AND

methodsEighty chronic periodontitis patients, 40 smokers and 40 non-smokers, were recruited to this single-arm clinical trial. Smoking status was validated by measuring serum cotinine levels. Periodontal examinations were performed at baseline (T0) and 3 months following non-surgical and surgical periodontal therapy (T1). At T0 and T1, subgingival plaque samples were collected from the deepest periodontal pocket in each patient and analysed using checkerboard DNA-DNA hybridization. Probing depth (PD) ≥ 5 mm with bleeding on probing (BoP) was defined as the primary outcome. Unadjusted and adjusted logistic regression analyses, corrected for clustered observations within patients and teeth, were conducted comparing smokers with non-smokers.

resultsClinical parameters significantly improved in both groups (p < 0.001). An association was revealed between smoking and PD ≥ 5 mm with BoP (OR= 1.90, CI: 1.14, 3.15, p = 0.013), especially for plaque-positive sites (OR= 4.14, CI: 2.16, 7.96, p < 0.001). A significant reduction of red complex microbiota was observed for non-smokers only (p = 0.010).

conclusionSmokers respond less favourably to non-surgical and surgical periodontal therapy compared with non-smokers, in particular at plaque-positive sites.

Indexed as

SmokingAdultAgedDental Plaque IndexFemaleHumansMaleMiddle AgedPeriodontal Attachment LossPeriodontal IndexPeriodontal PocketPeriodontitisTreatment Outcomechronic periodontitiscluster analysismicrobiologyperiodontal therapysmoking

Identifiers

PMID26407817
PMCPMC6207927

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.