Evidence map›Paper›PMID 26407604›Full record

ArticlePsychopharmacology2016

Effects of alcohol-induced working memory decline on alcohol consumption and adverse consequences of use.

William V Lechner, Anne M Day, Jane Metrik, Adam M Leventhal, Christopher W Kahler

Abstract read
In one paragraph

Article in Psychopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Menstrual cycle phase affects alcohol impairment of working memory.Alcohol, clinical & experimental research · 2025
    Trial
  4. Acute effect of alcohol on working memory updating.Addiction (Abingdon, England) · 2021
    Trial
  5. Trial
  6. Article
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  11. Review
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  14. On the role of (implicit) drinking self-identity in alcohol use and problematic drinking: A comparison of five measures.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2021
    Article
  15. Article
  16. Review
  17. Article
  18. Impulsivity, working memory, and impaired control over alcohol: A latent variable analysis.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

William V LechnerCenter for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, USA. william_lechner@brown.edu.
Anne M DayEdward Hines, Jr. VA Hospital, Hines, USA.
Jane MetrikCenter for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, USA.
Adam M LeventhalDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, USA.
Christopher W KahlerCenter for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, USA.

Funding

Substance Abuse Intervention/Outcome Research TrainingT32DA016184 · NIDA · BROWN UNIVERSITY · PI Damaris J. Rohsenow, JENNIFER W. TIDEY · 2003 to 2026
$6.1M
Mechanisms Linkng Alcohol Use and Smoking Relapse RiskR01AA016978 · NIAAA · BROWN UNIVERSITY · PI KAHLER, CHRISTOPHER W. · 2008 to 2011
$2.1M
NIAAA NIH HHS R01 AA016978NIAAA NIH HHS R01AA016978NIDA NIH HHS T32 DA016184
6 · The paper itself

Abstract

rationaleAlcohol use appears to decrease executive function acutely in a dose-dependent manner, and lower baseline executive function appears to contribute to problematic alcohol use. However, no studies, to our knowledge, have examined the relationship between individual differences in working memory (a subcomponent of executive function) after alcohol consumption and drinking behaviors and consequences.

objectivesThe current study assessed the relationship between drinking behavior, alcohol-related consequences, and alcohol-induced changes in working memory (as assessed by Trail Making Test-B).

methodParticipants recruited from the community (n = 41), 57.3 % male, mean age 39.2, took part in a three-session, within-subjects, repeated-measures design. Participants were administered a placebo, 0.4 g/kg, or 0.8 g/kg dose of alcohol. Working memory, past 30-day alcohol consumption, and consequences of alcohol use were measured at baseline; working memory was measured again after each beverage administration.

resultsPoorer working memory after alcohol administration (controlling for baseline working memory) was significantly associated with a greater number of drinks consumed per drinking day. Additionally, we observed a significant indirect relationship between the degree of alcohol-induced working memory decline and adverse consequences of alcohol use, which was mediated through greater average drinks per drinking day.

conclusionsIt is possible that greater individual susceptibility to alcohol-induced working memory decline may limit one's ability to moderate alcohol consumption as evidenced by greater drinks per drinking day and that this results in more adverse consequences of alcohol use.

Indexed as

AdultAgedAlcohol DrinkingEthanolFemaleHumansMaleMemory DisordersMemory, Short-TermMiddle AgedTrail Making TestYoung AdultEthanolAlcoholAlcohol abuseExecutive functionProblem drinkingWorking memory

Identifiers

PMID26407604
PMCPMC4703468

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.