ArticleJournal of the American Academy of Child and Adolescent Psychiatry2015
Antecedents of the child behavior checklist-dysregulation profile in children born extremely preterm.
Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Trial
- Count of Neonatal Morbidities Predicts Outcomes at Age 10 and 15 Years in Infants Born Extremely Preterm.The Journal of pediatrics · 2025Article
- Clinical correlates of emotion dysregulation in Down syndrome: a comparative study.Frontiers in psychology · 2025Article
- Association of Growth During Infancy with Neurodevelopment and Obesity in Children Born Very Preterm: The Environmental Influences on Child Health Outcomes Cohort.The Journal of pediatrics · 2024Article
- Maternal and psychosocial antecedents of anxiety and depression in extremely low gestational age newborns at age 15 years.Frontiers in child and adolescent psychiatry · 2024Article
- Perinatal Factors and Emotional, Cognitive, and Behavioral Dysregulation in Childhood and Adolescence.Journal of the American Academy of Child and Adolescent Psychiatry · 2023Article
- Assessment of Psychosocial and Neonatal Risk Factors for Trajectories of Behavioral Dysregulation Among Young Children From 18 to 72 Months of Age.JAMA network open · 2023Article
- Psychiatric Outcomes, Functioning, and Participation in Extremely Low Gestational Age Newborns at Age 15 Years.Journal of the American Academy of Child and Adolescent Psychiatry · 2022Article
- Associations between maternal pre-pregnancy body mass index and neonatal neurobehavior in infants born before 30 weeks gestation.Journal of perinatology : official journal of the California Perinatal Association · 2022Observational
- Trajectories of dysregulation in preschool age.European child & adolescent psychiatry · 2022Article
- Placental programming, perinatal inflammation, and neurodevelopment impairment among those born extremely preterm.Pediatric research · 2021Review
- Behavioral problems are associated with cognitive and language scores in toddlers born extremely preterm.Early human development · 2019Article
- Antecedents of Obesity Among Children Born Extremely Preterm.Pediatrics · 2018Observational
- Antecedents of Screening Positive for Attention Deficit Hyperactivity Disorder in Ten-Year-Old Children Born Extremely Preterm.Pediatric neurology · 2018Observational
- Predictive Validity of the Modified Checklist for Autism in Toddlers (M-CHAT) Born Very Preterm.The Journal of pediatrics · 2016Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
objectiveExtremely preterm newborns are at heightened risk for emotional and behavioral dysregulation later in childhood. Our goal was to systematically evaluate the antenatal and early postnatal antecedents that might mediate the association between extreme preterm birth and emotional and behavioral dysregulation at age 2 years (corrected age).
methodIn a multi-site prospective study, the parents of 826 infants born before 28 weeks gestation completed a Child Behavior Checklist (CBCL) when the child was 2 years corrected age. We compared the maternal, pregnancy, placenta, delivery, and newborn characteristics, as well as early postnatal characteristics and exposures of those who satisfied criteria for the CBCL-Dysregulation Profile (CBCL-DP) to those of their peers. We then used time-oriented logistic regression models, starting first with antenatal variables that distinguished children with the CBCL-DP profile from their peers, and then added the distinguishing postnatal variables.
resultsApproximately 9% of the children had a CBCL-DP. In the time-oriented logistic regression model with antenatal variables only, low maternal education achievement, passive smoking, and recovery of Mycoplasma from the placenta were associated with increased risk, whereas histologic chorioamnionitis was associated with reduced risk. None of the postnatal variables added statistically significant discriminating information.
conclusionVery preterm newborns who later manifest the CBCL-DP at age 2 years differ in multiple ways from their preterm peers who do not develop the CBCL-DP, raising the possibility that potentially modifiable antenatal and early postnatal phenomena contribute to the risk of developing emotional and behavioral dysregulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.