Evidence map›Paper›PMID 26407411›Full record

SynthesisJournal of the Pediatric Infectious Diseases Society2015

Neonatal Herpes Simplex Virus Type 1 Infection and Jewish Ritual Circumcision With Oral Suction: A Systematic Review.

Brian F Leas, Craig A Umscheid

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Journal of the Pediatric Infectious Diseases Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. A Review of Infectious Diseases Associated with Religious and Nonreligious Rituals.Interdisciplinary perspectives on infectious diseases · 2021
    Review
  2. Article
  3. Article
  4. Management of OcularComparative medicine · 2018
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Brian F LeasCenter for Evidence-Based Practice.
Craig A UmscheidCenter for Evidence-Based Practice Department of Medicine Center for Clinical Epidemiology and Biostatistics Leonard Davis Institute of Health Economics Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia.
Center for Clinical Research (United States) · US

Funding

INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR024134 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2006 to 2011
$70.4M
Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
NCATS NIH HHS UL1 TR000003NCATS NIH HHS UL1TR000003NCRR NIH HHS UL1 RR024134NCRR NIH HHS UL1RR024134
6 · The paper itself

Abstract

Jewish ritual circumcision rarely but occasionally includes a procedure involving direct oral suction of the wound, which can expose an infant to infection with herpes simplex virus type 1 (HSV-1). This practice has provoked international controversy in recent years, but no systematic review of the clinical literature has previously been published. We designed this review to identify and synthesize all published studies examining the association between circumcision with direct oral suction and HSV-1 infection. Our search strategy identified 6 published case series or case reports, documenting 30 cases between 1988 and 2012. Clinical findings were consistent with transmission of infection during circumcision, although the evidence base is limited by the small number of infections and incomplete case data. Published evidence suggests that circumcision with direct oral suction has resulted in severe neonatal illness and death from HSV-1 transmission, but further research is necessary to clarify the risk of infection.

Indexed as

JudaismRisk AssessmentCeremonial BehaviorCircumcision, MaleHerpes SimplexHerpesvirus 1, HumanHumansInfant, NewbornJewsMaleSuctioncircumcisionherpes simplex virusneonatal

Identifiers

PMID26407411
PMCPMC4608492
OpenAlexW2141065472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.