Evidence map›Paper›PMID 26407358›Full record

ReviewJournal of the Pediatric Infectious Diseases Society2015

Lessons Learned in Antibiotic Stewardship: Fluoroquinolone Use in Pediatrics.

Adam L Hersh, Jeffrey S Gerber, Lauri A Hicks, Andrew T Pavia

Abstract readReview
In one paragraph

Review in Journal of the Pediatric Infectious Diseases Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Outpatient Fluoroquinolone Use in Children, 2000-2018.Journal of the Pediatric Infectious Diseases Society · 2021
    Article
  4. Review
  5. Creation of a Combination Antibiogram forThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2021
    Article
  6. Article
  7. Article
  8. Safety Concerns Surrounding Quinolone Use in Children.Journal of clinical pharmacology · 2016
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adam L HershDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah, Salt Lake City;
Jeffrey S GerberDivision of Infectious Diseases, Department of Pediatrics and The Center for Pediatric Clinical Effectiveness, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia;
Lauri A HicksRespiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Andrew T PaviaDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah, Salt Lake City;

Funding

An Automated Multi-target Diagnostic System for Gastrointestinal PathogensR01AI089489 · NIAID · BIOFIRE DEFENSE, LLC. · PI ROGATCHEVA, MARGARITA B · 2010 to 2012
$3.3M
Electronic Surveillance for Wound Infections after Ambulatory Pediatric SurgeryR01HS020921 · AHRQ · CHILDREN'S HOSP OF PHILADELPHIA · PI COFFIN, SUSAN MD · 2011 to 2015
$2.5M
Epidemiology and Etiology of Hospitalized Pneumonia in ChildrenU18IP000491 · IP · UNIVERSITY OF UTAH · PI AMPOFO, KROW · 2011 to 2013
$950k
AHRQ HHS 1R01HS20921-01AHRQ HHS R01 HS020921NCIRD CDC HHS 1U18IP000491NCIRD CDC HHS U18 IP000491NIAID NIH HHS 1R01AI089489-01NIAID NIH HHS R01 AI089489PHS HHS 11IPA110369
6 · The paper itself

Abstract

The use of fluoroquinolones differs dramatically between adult and pediatric patients. For adults, they are the leading class of antibiotics prescribed in ambulatory care visits whereas in children, they are the least frequently prescribed class. The reasons for this difference in practice likely relate to perceptions of their potential for harm. This highlights the impact of physicians' perception of direct patient harm in antibiotic decision making which has implications for antibiotic stewardship.

Indexed as

Anti-Bacterial AgentsChildDrug Resistance, MicrobialFluoroquinolonesHumansPediatricsPractice Patterns, Physicians'Anti-Bacterial AgentsFluoroquinolonesantibacterial agentsdrug resistancephysician's practice patterns.

Identifiers

PMID26407358
PMCPMC5965879

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.