Evidence map›Paper›PMID 26406362›Full record

ArticleCell2015

Morgan's legacy: fruit flies and the functional annotation of conserved genes.

Hugo J Bellen, Shinya Yamamoto

Erratum issuedAbstract readHistorical Article
In one paragraph

Article in Cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. A Landscape ofBiology · 2026
    Review
  2. Functional assays inGenome research · 2025
    Review
  3. Article
  4. Review
  5. Diversity ofFrontiers in cell and developmental biology · 2025
    Article
  6. Review
  7. Pathogens (Basel, Switzerland) · 2024
    Review
  8. Article
  9. The fruit flyFrontiers in pharmacology · 2024
    Article
  10. AlternativeFrontiers in cellular and infection microbiology · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. An optimized temporally controlled Gal4 system inFrontiers in neuroscience · 2023
    Article
  15. Model organisms for functional validation in genetic renal disease.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Role ofInternational journal of molecular sciences · 2022
    Article
  20. Disease Modeling of Rare Neurological Disorders in Zebrafish.International journal of molecular sciences · 2022
    Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

2 authors.

Hugo J BellenProgram in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA; Howard Hughes Medical Institute (HHMI), Houston, TX, 77030, USA. Electronic address: hbellen@bcm.edu.
Shinya YamamotoProgram in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.

Funding

Transposon induced disruption of most Drosophila genesR01GM067858 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J · 2003 to 2020
$15.7M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM067858
6 · The paper itself

Abstract

In 1915, "The Mechanism of Mendelian Heredity" was published by four prominent Drosophila geneticists. They discovered that genes form linkage groups on chromosomes inherited in a Mendelian fashion and laid the genetic foundation that promoted Drosophila as a model organism. Flies continue to offer great opportunities, including studies in the field of functional genomics.

Indexed as

AnimalsDrosophila melanogasterGeneticsGenetic TechniquesHistory, 20th CenturyHumansModels, Animal

Identifiers

PMID26406362
PMCPMC4783153

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.