ReviewJournal of Parkinson's disease2015
Alcohol Consumption and Parkinson's Disease Risk: A Review of Recent Findings.
Review in Journal of Parkinson's disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association Between Visual Impairment and Depression in Patients Attending Eye Clinics: A Meta-analysis.JAMA ophthalmology · 2021Pooled it
- Parkinson's Disease Risk and Alcohol Intake: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies.Frontiers in nutrition · 2021Pooled it
- Alcohol consumption and risk for Parkinson's disease: a systematic review and meta-analysis.Journal of neurology · 2019Pooled it
- Trial
- Early alcohol initiation is associated with higher lifetime Parkinson's disease risk after accounting for exposure latency.Journal of Parkinson's disease · 2026Article
- Consensus Molecules Associated with Parkinson's Disease.Neurology international · 2026Review
- Association between alcohol consumption and mortality in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Liver fibrosis associated with more severe motor deficits in early Parkinson's disease.Clinical neurology and neurosurgery · 2025Article
- Associations of the Life's Essential 8 with Parkinson's disease: a population-based study.Frontiers in aging neuroscience · 2025Article
- Epigenetic associations ofFrontiers in psychiatry · 2024Article
- Correlation between dietary factors and Parkinson's disease revealed by the analysis of Mendelian randomization.Frontiers in nutrition · 2024Article
- Screening and Targeting Risk Factors for Prodromal Synucleinopathy: Taking Steps toward a Prescriptive Multi-modal Framework.Aging and disease · 2023Review
- Polytherapy and Multimorbidity Pattern of Users of Anti-VEGF Drugs and Dexamethasone for the Treatment of Age-Related Macular Degeneration and other Vascular Retinopathies in Clinical Practice.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Changes in smoking, alcohol consumption, and the risk of Parkinson's disease.Frontiers in aging neuroscience · 2023Article
- The Association between Vision Impairment and Depression: A Systematic Review of Population-Based Studies.Journal of clinical medicine · 2022Review
- Article
- Association of Physical Activity, Including Amount and Maintenance, With All-Cause Mortality in Parkinson Disease.JAMA neurology · 2021Article
- NOGEA: A Network-oriented Gene Entropy Approach for Dissecting Disease Comorbidity and Drug Repositioning.Genomics, proteomics & bioinformatics · 2021Article
- Article
- Deep learning in systems medicine.Briefings in bioinformatics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe association between Parkinson's disease and lifestyle exposures such as smoking, coffee and alcohol consumption have been the focus of research for several decades, with varying and often conflicting results.
objectiveThis paper reviews the key features of observational studies investigating the relationship between alcohol drinking and PD risk, to determine potential sources of variability between the results.
methodsRelevant literature from 2000-2014 was systematically retrieved using three databases. Primary research articles were included if they reported a measure of association between quantity and frequency of alcohol intake and PD risk, and adjusted at least for the potential confounding factors of smoking and age.
resultsSixteen articles were identified. The seven case-control studies were more likely to report a weak protective association by level of alcohol consumption compared to the studies with prospective designs. Two studies reported the relationship between heavy (harmful to health) drinking and PD. There was weak evidence that associations varied by type of alcoholic beverage. Smoking may modify the association between alcohol intake and PD risk, however, the evidence does not support the theory that a confounder (such as an addiction-avoiding personality trait) produced the inverse associations between smoking, coffee and alcohol intake and PD risk. Methodological weaknesses of the studies, including selection and recall bias, residual confounding and lack of statistical power may in part account for their differences.
conclusionThe weak association between alcohol drinking and PD risk was found in studies at greater risk of selection and recall bias.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.