ArticlePloS one2015
Microbiological Surveillance of Peritoneal Dialysis Associated Peritonitis: Antimicrobial Susceptibility Profiles of a Referral Center in GERMANY over 32 Years.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 45 citations in OpenAlex.
- Changing microbiology and outcomes of PD-associated peritonitis over four decades.Clinical kidney journal · 2026Article
- Flying under the radar: vancomycin heteroresistance inASM case reports · 2025Article
- Microbiological Surveillance and Antimicrobial Susceptibility Observations on Peritoneal Dialysis-Associated Peritonitis in an Outpatient German Reference Center.Infectious disease reports · 2025Article
- Epidemiology, drug resistance, and clinical risk factors of peritoneal dialysis-associated peritonitis: a five-year multicenter study.Frontiers in cellular and infection microbiology · 2025Article
- Clinical characteristics and antibiotic treatment of peritoneal dialysis-associated peritonitis caused byMicrobiology spectrum · 2024Article
- Pathogenic spectrum and risk factors of peritoneal dialysis-associated peritonitis: a single-center retrospective study.BMC infectious diseases · 2024Article
- Evolution of Peritoneal Dialysis-Associated Peritonitis: Pathogen, Antibiotic Resistance, and the Impact of Lymphocyte Count on Treatment Outcomes.Infection and drug resistance · 2024Article
- The effect of rural and urban life on peritonitis rates in chronic peritoneal patients.Renal failure · 2023Article
- Predictive Factors, Treatment, and Outcomes of Coagulase-Negative Staphylococcal Peritonitis in Malaysian Peritoneal Dialysis Patients: A Single-Center Study.International journal of nephrology · 2022Article
- Peritoneal dialysis-related peritonitis caused by gram-negative organisms: ten-years experience in a single center.Renal failure · 2021Article
- Intraperitoneal Antibiotic Utilization among Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients with Peritonitis at a Tertiary Hospital Setting in Malaysia.Journal of pharmacy & bioallied sciences · 2020Article
- Article
- Antimicrobial resistance in nephrology.Nature reviews. Nephrology · 2019Review
- Article
- Benefit of an operating vehicle preventing peritonitis in peritoneal dialysis patients: a retrospective, case-controlled study.International urology and nephrology · 2018Article
- A Case of Relapsing Peritoneal Dialysis-Associated Peritonitis byCase reports in infectious diseases · 2018Article
- Peritoneal dialysis-related infections recommendations: 2016 update. What is new?International urology and nephrology · 2017Review
- ISPD Peritonitis Recommendations: 2016 Update on Prevention and Treatment.Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis · 2016Review
- Newer antibiotics for the treatment of peritoneal dialysis-related peritonitis.Clinical kidney journal · 2016Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPeritonitis is one of the most important causes of treatment failure in peritoneal dialysis (PD) patients. This study describes changes in characteristics of causative organisms in PD-related peritonitis and antimicrobial susceptibility.
methodsIn this single center study we analyzed retrospective 487 susceptibility profiles of the peritoneal fluid cultures of 351 adult patients with peritonitis from 1979 to 2014 (divided into three time periods, P1-P3).
resultsStaphylococcus aureus decreased from P1 compared to P2 and P3 (P<0.05 and P<0.01, respectively). Methicillin-resistant S. aureus (MRSA) occurred only in P3. Methicillin-resistant Staphylococcus epidermidis (MRSE) increased in P3 over P1 and P2 (P <0.0001, respectively). In P2 and P3, vancomycin resistant enterococci were detected. The percentage of gram-negative organisms remained unchanged. Third generation cephalosporin resistant gram-negative rods (3GCR-GN) were found exclusively in P3. Cefazolin-susceptible gram-positive organisms decreased over the three decades (93% in P1, 75% in P2 and 58% in P3, P<0.01, P<0.05 and P<0.0001, respectively). Vancomycin susceptibility decreased and gentamicin susceptibility in gram-negatives was 94% in P1, 82% in P2 and 90% in P3. Ceftazidim susceptibility was 84% in P2 and 93% in P3.
conclusionsPeritonitis caused by MSSA decreased, but peritonitis caused by MRSE increased. MRSA peritonitis is still rare. Peritonitis caused by 3GCR-GN is increasing. An initial antibiotic treatment protocol should be adopted for PD patients to provide continuous surveillance.
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