Evidence map›Paper›PMID 26405621›Full record

ArticleSpringerPlus2015

Tamoxifen retinopathy: a case report.

Lingling Wang, Heng Miao, Xiaoxin Li

Open access · diamondAbstract read
In one paragraph

Article in SpringerPlus, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Foveal cone loss in tamoxifen maculopathy: a case report.Journal of medical case reports · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. [Zoledronate-induced panuveitis].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lingling WangDepartment of Ophthalmology, Peking University People's Hospital, Xizhimen South Street 11, 100044 Beijing, China ; Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China ; Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China.
Heng MiaoDepartment of Ophthalmology, Peking University People's Hospital, Xizhimen South Street 11, 100044 Beijing, China ; Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China ; Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China.
Xiaoxin LiDepartment of Ophthalmology, Peking University People's Hospital, Xizhimen South Street 11, 100044 Beijing, China ; Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China ; Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China.ORCID 0000-0002-5161-9458
Ministry of Education of the People's Republic of China · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo present a case of tamoxifen retinopathy on a 57-year-old woman.

designAn observational case.

methodsA review of history, clinical examination, and findings on Spectral-domain Optical Coherence Tomography (SD-OCT), fluorescein angiogram (FA) and electro-oculogram (EOG) was conducted.

resultsA 57-year old female patient, who had been treated with oral tamoxifen after mastectomy due to breast cancer, had profound visual impairment in both eyes. Disruption of the ellipsoid zone and interdigitation zone which represent photoreceptor damage as well as macular thinning was revealed on SD-OCT in both eyes. Bilateral retinal pigmented epithelium (RPE) function compromised was indicated by reduced Arden ratio in EOG.

conclusionTamoxifen-induced retinopathy could be detected by SD-OCT and EOG. As it is irreversible, patients who are given tamoxifen need regular ophthalmic consultation, including SD-OCT and EOG before and during the treatment in order to early detect and avoid further retinal damage.

Indexed as

Electro-oculogramRetinopathySpectral-domain optical coherence tomographyTamoxifen

Identifiers

PMID26405621
PMCPMC4573752
OpenAlexW1933759592

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.