Evidence map›Paper›PMID 26405147›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015

Patterns of Hydrocephalus Caused by Congenital Toxoplasma gondii Infection Associate With Parasite Genetics.

Samuel L Hutson, Kelsey M Wheeler, David McLone, David Frim, Richard Penn, Charles N Swisher, Peter T Heydemann, Kenneth M Boyer, A Gwendolyn Noble, Peter Rabiah and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 54 citations in OpenAlex.

  1. Trial
  2. Transplacental Infection: Frequency, Testing, and Treatment.Deutsches Arzteblatt international · 2026
    Review
  3. Article
  4. Global geographical distribution ofParasite epidemiology and control · 2025
    Review
  5. Article
  6. Article
  7. Toxoplasma gondii infections in pediatric neurosurgery.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Frontiers in cellular and infection microbiology · 2021
    Article
  16. Not all ventriculomegaly is created equal: diagnostic overview of fetal, neonatal and pediatric ventriculomegaly.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020
    Review
  17. Article
  18. Article
  19. Predictors ofInternational journal of pediatrics · 2020
    Article
  20. Serotyping ofFrontiers in cellular and infection microbiology · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 1 country.

Samuel L HutsonDepartment of Ophthalmology and Visual Science, The University of Chicago.
Kelsey M WheelerDepartment of Ophthalmology and Visual Science, The University of Chicago.
David McLoneNorthwestern University and Lurie Children's Hospital and Medical Center.
David FrimSection of Neurosurgery, The University of Chicago.
Richard PennDepartment of Bioengineering, College of Engineering, College of Medicine, University of Illinois at Chicago.
Charles N SwisherNorthwestern University and Lurie Children's Hospital and Medical Center.
Peter T HeydemannDepartment of Pediatrics, Rush University Medical Center, Chicago.
Kenneth M BoyerDepartment of Pediatrics, Rush University Medical Center, Chicago.
A Gwendolyn NobleNorthwestern University and Lurie Children's Hospital and Medical Center.
Peter RabiahNorth Shore University Hospital, Evanston, Illinois.
Shawn WithersDepartment of Ophthalmology and Visual Science, The University of Chicago.
Jose G MontoyaDivision of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, California.
Kristen WroblewskiDepartment of Public Health Sciences, The University of Chicago, Illinois.
Theodore KarrisonDepartment of Public Health Sciences, The University of Chicago, Illinois.
Michael E GriggLaboratory of Parasitic Diseases, NIAID, National Institutes of Health, Bethesda, Maryland.
Rima McLeodDepartment of Ophthalmology and Visual Science, The University of Chicago.
University of Chicago · USChildren's Hospital & Medical Center · USRush University Medical Center · USChicago Department of Public Health · USNational Institute of Allergy and Infectious Diseases · USNorthShore University HealthSystem · USStanford University · USUniversity of Illinois Chicago · US

Funding

Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
Toxoplasma Surface Antigens and ImmunityZIAAI001017 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GRIGG, MICHAEL · 2009 to 2025
$9.9M
TREATMENT OF CONGENITAL TOXOPLASMOSISR01AI027530 · NIAID · UNIVERSITY OF CHICAGO · PI MCLEOD, RIMA L · 1989 to 2010
$2.8M
Intramural NIH HHSNCATS NIH HHS UL1 TR000430NIAID NIH HHS R01 AI027530NIAID NIH HHS R01 AI27530
6 · The paper itself

Abstract

Four anatomical patterns of hydrocephalus secondary to congenital Toxoplasma gondii infection were identified and characterized for infants enrolled in the National Collaborative Chicago-based Congenital Toxoplasmosis Study. Analysis of parasite serotype revealed that different anatomical patterns associate with Type-II vs Not-Exclusively Type-II strains (NE-II) (P = .035).

Indexed as

GenotypeCohort StudiesHumansHydrocephalusSerogroupToxoplasmaToxoplasmosis, Congenitalaqueductal obstructionforaminal obstructionhydrocephalusToxoplasma gondii

Identifiers

PMID26405147
PMCPMC4657535
OpenAlexW2221608780

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.