Evidence map›Paper›PMID 26405081›Full record

ArticleAJNR. American journal of neuroradiology2016

Evaluation of the Angiographic Grading Scale in Aneurysms Treated with the WEB Device in 80 Rabbits: Correlation with Histologic Evaluation.

A Rouchaud, W Brinjikji, Y-H Ding, D Dai, Y Q Zhu, H J Cloft, D F Kallmes, R Kadirvel

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Persistent flow inside the Woven EndoBridge at angiographic follow-up: A multicenter study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  7. The impact of pre-treatment aneurysm angulation. What happens with WEB devices at follow-up?Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  8. Article
  9. Article
  10. Impact of aneurysm diameter, angulation, and device sizing on complete occlusion rates using the woven endobridge (WEB) device: Single center United States experience.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023
    Article
  11. Article
  12. WEB Device Shape Changes in Elastase-Induced Aneurysms in Rabbits.AJNR. American journal of neuroradiology · 2021
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

A RouchaudFrom the Neuroradiology Research Laboratory (A.R., Y.-H.D., D.D., Y.Q.Z., D.F.K., R.K.), Mayo Clinic College of Medicine, Rochester, Minnesota the Department of Radiology (A.R., W.B., H.J.C., D.F.K.), Mayo Clinic, Rochester, Minnesota. Rouchaud.Aymeric@mayo.edu aymeric.rouchaud@gmail.com.ORCID http://orcid.org/0000-0003-0902-3375
W Brinjikjithe Department of Radiology (A.R., W.B., H.J.C., D.F.K.), Mayo Clinic, Rochester, Minnesota.ORCID http://orcid.org/0000-0001-5271-5524
Y-H DingFrom the Neuroradiology Research Laboratory (A.R., Y.-H.D., D.D., Y.Q.Z., D.F.K., R.K.), Mayo Clinic College of Medicine, Rochester, Minnesota.ORCID http://orcid.org/0000-0003-4329-3192
D DaiFrom the Neuroradiology Research Laboratory (A.R., Y.-H.D., D.D., Y.Q.Z., D.F.K., R.K.), Mayo Clinic College of Medicine, Rochester, Minnesota.ORCID http://orcid.org/0000-0003-4051-6450
Y Q ZhuFrom the Neuroradiology Research Laboratory (A.R., Y.-H.D., D.D., Y.Q.Z., D.F.K., R.K.), Mayo Clinic College of Medicine, Rochester, Minnesota.ORCID http://orcid.org/0000-0001-5476-9075
H J Cloftthe Department of Radiology (A.R., W.B., H.J.C., D.F.K.), Mayo Clinic, Rochester, Minnesota.ORCID http://orcid.org/0000-0003-2590-3815
D F KallmesFrom the Neuroradiology Research Laboratory (A.R., Y.-H.D., D.D., Y.Q.Z., D.F.K., R.K.), Mayo Clinic College of Medicine, Rochester, Minnesota the Department of Radiology (A.R., W.B., H.J.C., D.F.K.), Mayo Clinic, Rochester, Minnesota.ORCID http://orcid.org/0000-0002-8495-0040
R KadirvelFrom the Neuroradiology Research Laboratory (A.R., Y.-H.D., D.D., Y.Q.Z., D.F.K., R.K.), Mayo Clinic College of Medicine, Rochester, Minnesota.ORCID http://orcid.org/0000-0002-6786-9953
Mayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe WEB Occlusion Score has been proposed to assess angiographic outcomes for intracranial aneurysms treated with the Woven EndoBridge (WEB) device. Using a large series of experimental aneurysms treated with the WEB, we had the following objectives: 1) to compare angiographic outcomes as measured by the WEB Occlusion Scale with histologic results, and 2) to assess interobserver and intraobserver agreement of the WEB Occlusion Scale. MATERIALS AND

methodsIntracranial aneurysms were created in 80 rabbits and treated with WEB devices. Animals were sacrificed at last follow-up for histologic evaluation. DSA was performed just after the deployment of the device and at follow-up. Four investigators independently and retrospectively graded the DSA twice according to the WEB Occlusion Scale. One histopathologist blinded to the angiographic results graded the occlusion according to a 4-point scale patterned on the WEB Occlusion Scale. Intra- and interobserver agreement were evaluated for DSA. Follow-up angiographic grading and histologic reference were compared to determine the WEB Occlusion Scale accuracy for complete (with or without recess filling) versus incomplete occlusion and adequate (complete occlusion or neck remnant) versus inadequate occlusion.

resultsInter- and intraobserver weighted κ for the angiographic WEB Occlusion Scale were, respectively, 0.76 and 0.76, indicating substantial agreement. The sensitivity and specificity of the WEB Occlusion Scale for complete occlusion at follow-up compared with the histologic reference standard were, respectively, 75% and 83.3%, with an overall accuracy of 80%. Similarly, for adequate occlusion at follow-up, sensitivity was 97.7%, specificity was 64.9%, and overall accuracy was 82.5%.

conclusionsThe WEB Occlusion Scale appears to be consistent, reliable, and accurate compared with a histologic reference standard.

Indexed as

AnimalsCerebral AngiographyDisease Models, AnimalEmbolization, TherapeuticEndovascular ProceduresFemaleIntracranial AneurysmObserver VariationRabbitsRetrospective StudiesSensitivity and SpecificityTreatment Outcome

Identifiers

PMID26405081
PMCPMC7959938
OpenAlexW2287414880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.