Evidence map›Paper›PMID 26404858›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2016

Nutrition intervention approaches to reduce malnutrition in oncology patients: a systematic review.

Jia Li Charmaine Lee, Lai Peng Leong, Su Lin Lim

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 6 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 6 syntheses or guidelines pooled it, 125 citations in OpenAlex.

  1. Pooled it
  2. Multimodal interventions for cachexia management.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. SEOM clinical guidelines for cancer anorexia-cachexia syndrome (2023).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Guideline
  6. Guideline
  7. Trial
  8. Trial
  9. Protein intake, weight loss, dietary intervention, and worsening of quality of life in older patients during chemotherapy for cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Trial
  10. Trial
  11. Long-term follow-up of the potential benefits of early nutritional intervention in adults with upper gastrointestinal cancer: a pilot randomised trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Trial
  12. Trial
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jia Li Charmaine LeeFood Science and Technology Programme, Department of Chemistry, National University of Singapore, Singapore, 117543, Singapore.
Lai Peng LeongFood Science and Technology Programme, Department of Chemistry, National University of Singapore, Singapore, 117543, Singapore.
Su Lin LimDietetics Department, National University Hospital, 5 Lower Kent Ridge Road, Main Building, Singapore, 119074, Singapore. su_lin_lim@nuhs.edu.sg.
National University of Singapore · SGNational University Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMalnutrition is a very common problem in oncology patients and is associated with many negative consequences including poorer prognosis, quality of life and survival. However, malnutrition in oncology patients is often overlooked although there is growing evidence showing that it can be prevented or reduced through nutrition intervention. This paper aims to provide an updated review on the effectiveness of different nutrition intervention approaches on nutrition status outcomes in oncology patients.

methodsRandomised controlled trials (RCTs) published between 1994 and 2014 which examined the effects of nutrition intervention approaches--in particular, nutrition counselling (NC), oral nutrition supplements (ONS) and tube feeding (TF)--on nutrition status outcomes of oncology patients were identified and reviewed.

resultsThirteen papers from 11 RCTs with a total of 1077 participants were included. The intervention approaches included NC (four studies), NC + ONS (five studies), ONS (three studies) and TF (three studies). The various results suggest that NC with or without ONS was associated with consistent improvements in several nutrition status outcomes. On the other hand, ONS and TF were associated with inconsistent improvements in few aspects of nutrition status outcomes.

conclusionsThe referral of oncology patients for NC is recommended given the strong evidence of its beneficial effects on the prevention and reduction of malnutrition. Other forms of nutrition support including ONS and TF may then be included if deemed suitable and necessary for the individual.

Indexed as

Nutritional SupportCounselingDietary SupplementsEnteral NutritionHumansMalnutritionMiddle AgedNeoplasmsQuality of LifeCancerNutrition counsellingNutrition interventionNutrition statusOral nutrition supplementsTube feeding

Identifiers

PMID26404858
OpenAlexW2143215269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.