Evidence map›Paper›PMID 26404727›Full record

ReviewCurrent neurology and neuroscience reports2015

Super-Refractory Status Epilepticus.

Mauricio Ruiz Cuero, Panayiotis N Varelas

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current neurology and neuroscience reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Updates in Refractory Status Epilepticus.Critical care research and practice · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mauricio Ruiz CueroNeurocritical Care Services, Department of Neurology, Henry Ford Hospital, K-11, 2799 West Grand Blvd, Detroit, MI, 48202, USA. mruiz1@hfhs.org.
Panayiotis N VarelasNeurocritical Care Services, Department of Neurology, Henry Ford Hospital, K-11, 2799 West Grand Blvd, Detroit, MI, 48202, USA. pvarela1@hfhs.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the vast majority of patients with status epilepticus (SE) respond fairly well to the first- or second-line anti-epileptics, a minority require anesthetic agents to put the seizures under control. An even smaller number of patients do not even respond to those and constitute the subgroup of super-refractory SE. Because of the small numbers, there are no definitive studies regarding its etiology, pathophysiology, and treatment, and those are still based on expert opinions. Encephalitides, either infectious, autoimmune, or paraneoplastic may be the main etiological factors. Induced pharmacological coma, immunosuppression, electrical brain stimulation, hypothermia, and ketamine are few of the newer but unproven therapeutic approaches that should be considered.

Indexed as

AnimalsAnticonvulsantsAutoimmunityHumansSeizuresStatus EpilepticusTreatment OutcomeAnticonvulsantsAutoimmuneBarbituratesEncephalitisKetamineStatus epilepticusSuper refractory

Identifiers

PMID26404727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.