ArticleArchives of gynecology and obstetrics2016
Cord blood vitamin D status and neonatal outcomes in a birth cohort in Quebec, Canada.
Article in Archives of gynecology and obstetrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Data resource profile: a nationally representative linked pregnancy cohort in Canada integrating clinical, social, and environmental data.International journal of population data science · 2023Article
- Correction of neonatal vitamin D status using 1000 IU vitamin D/d increased lean body mass by 12 months of age compared with 400 IU/d: a randomized controlled trial.The American journal of clinical nutrition · 2022Article
- Associations of Vitamin D Deficiency, Parathyroid hormone, Calcium, and Phosphorus with Perinatal Adverse Outcomes. A Prospective Cohort Study.Nutrients · 2020Article
- Association between umbilical cord vitamin D levels and adverse neonatal outcomes.The Journal of international medical research · 2020Article
- Prevalence of Vitamin D Deficiency in a Large Newborn Cohort from Northern United States and Effect of Intrauterine Drug Exposure.Nutrients · 2020Article
- Vitamin D Status in Pregnant Women in Southern China and Risk of Preterm Birth: A Large-Scale Retrospective Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Association between vitamin D level at birth and respiratory morbidities in very-low-birth-weight infants.Korean journal of pediatrics · 2019Article
- Maternal Vitamin D Deficiency and the Risk of Small for Gestational Age: A Meta-analysis.Iranian journal of public health · 2018Review
- Vitamin D and its impact on maternal-fetal outcomes in pregnancy: A critical review.Critical reviews in food science and nutrition · 2018Review
- Association between Vitamin Intake during Pregnancy and Risk of Small for Gestational Age.Nutrients · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
purposeSome evidence suggests that low maternal vitamin D status adversely affects perinatal health but few studies have examined cord blood vitamin D status. This project aimed to determine the association between the cord blood concentration of 25-hydroxyvitamin D [25(OH)D] and neonatal outcomes.
methodsA nested case-control study was conducted in Quebec City, Canada from 2005 to 2010. Included were 83 cases of low birthweight (LBW; <2500 g), 301 cases of small for gestational age (SGA; <10th percentile), 223 cases of preterm birth (PTB; <37 weeks' gestation), and 1027 controls. Levels of 25(OH)D were determined by chemiluminescence immunoassay. Adjusted odds ratios (OR) and 95 % confidence intervals (CI) were estimated with logistic regression.
resultsCord blood [25(OH)D] <50 nmol/L was associated with a lower risk of LBW compared to [25(OH)D] ≥75 nmol/L (OR 0.47 95 % CI 0.23-0.97). For 25(OH)D levels 50-75 nmol/L, a significant association was not demonstrated (OR 0.58, 95 % CI 0.34-1.01). No significant associations were observed between [25(OH)D] and either SGA or PTB after adjustment.
conclusionsAlthough our findings suggest that [25(OH)D] <50 nmol/L is associated with reduced risk of having a LBW infant, prenatal vitamin D recommendations require an examination of the literature that considers the full spectrum of maternal and neonatal outcomes.
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