Evidence map›Paper›PMID 26404389›Full record

ReviewBiomolecules2015

Combinatorial Control of mRNA Fates by RNA-Binding Proteins and Non-Coding RNAs.

Valentina Iadevaia, André P Gerber

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Understanding species-specific and conserved RNA-protein interactionsbioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. RNA binding proteins in MLL-rearranged leukemia.Experimental hematology & oncology · 2022
    Review
  13. RNA-binding proteins in diabetic microangiopathy.Journal of clinical laboratory analysis · 2022
    Review
  14. Review
  15. Modulation of miRISC-Mediated Gene Silencing in Eukaryotes.Frontiers in molecular biosciences · 2022
    Review
  16. Article
  17. Synergistic regulation ofRNA biology · 2021
    Article
  18. MiR-124 synergism with ELAVL3 enhances target gene expression to promote neuronal maturity.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  19. Article
  20. RNA-binding proteins in human genetic disease.Nature reviews. Genetics · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Valentina IadevaiaDepartment of Microbial & Cellular Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK. v.iadevaia@surrey.ac.uk.
André P GerberDepartment of Microbial & Cellular Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK. a.gerber@surrey.ac.uk.
University of Surrey · GB

Funding

Biotechnology and Biological Sciences Research Council BB/K009303/1
6 · The paper itself

Abstract

Post-transcriptional control of gene expression is mediated by RNA-binding proteins (RBPs) and small non-coding RNAs (e.g., microRNAs) that bind to distinct elements in their mRNA targets. Here, we review recent examples describing the synergistic and/or antagonistic effects mediated by RBPs and miRNAs to determine the localisation, stability and translation of mRNAs in mammalian cells. From these studies, it is becoming increasingly apparent that dynamic rearrangements of RNA-protein complexes could have profound implications in human cancer, in synaptic plasticity, and in cellular differentiation.

Indexed as

AnimalsHumansRNA-Binding ProteinsRNA, MessengerRNA, UntranslatedRNA-Binding ProteinsRNA, MessengerRNA, Untranslatedcombinatorial controlgene expressionmicroRNApost-transcriptional controlribonucleoprotein complexRNA-binding protein

Identifiers

PMID26404389
PMCPMC4693235
OpenAlexW2154730237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.