Evidence map›Paper›PMID 26404269›Full record

ArticleSensors (Basel, Switzerland)2015

Synergy Effect of Nanocrystalline Cellulose for the Biosensing Detection of Glucose.

Chakavak Esmaeili, Mahnaz M Abdi, Aji P Mathew, Mehdi Jonoobi, Kristiina Oksman, Majid Rezayi

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 96 citations in OpenAlex.

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  3. Cellulose-Based Electrochemical Sensors.Sensors (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Chakavak EsmaeiliSchool of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, UKM, 43600 Bangi, Malaysia. chakavak486@yahoo.com.
Mahnaz M AbdiDepartment of Chemistry, Faculty of Science, University Putra Malaysia, 43400 Serdang, Malaysia. mahnaz@upm.edu.my.
Aji P MathewDivision of Materials Science, Composite Centre Sweden, Lulea University of Technology, 97187 Lulea, Sweden. aji.mathew@ltu.se.
Mehdi JonoobiDepartment of Wood and Paper Science and Technology, Faculty of Natural Resources, University of Tehran, P.O. Box 31585-4313, 31587-77871 Karaj, Iran. mehdi.jonoobi@ut.ac.ir.
Kristiina OksmanDivision of Materials Science, Composite Centre Sweden, Lulea University of Technology, 97187 Lulea, Sweden. kristiina.oksman@ltu.se.
Majid RezayiChemistry Department, Faculty of Science, University Malaya, 50603 Kuala Lumpur, Malaysia. chem_rezayi@yahoo.com.
Luleå University of Technology · SENational University of Malaysia · MYUniversiti Putra Malaysia · MYUniversity of Applied Science and Technology · IRUniversity of Malaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrating polypyrrole-cellulose nanocrystal-based composites with glucose oxidase (GOx) as a new sensing regime was investigated. Polypyrrole-cellulose nanocrystal (PPy-CNC)-based composite as a novel immobilization membrane with unique physicochemical properties was found to enhance biosensor performance. Field emission scanning electron microscopy (FESEM) images showed that fibers were nanosized and porous, which is appropriate for accommodating enzymes and increasing electron transfer kinetics. The voltammetric results showed that the native structure and biocatalytic activity of GOx immobilized on the PPy-CNC nanocomposite remained and exhibited a high sensitivity (ca. 0.73 μA·mM(-1)), with a high dynamic response ranging from 1.0 to 20 mM glucose. The modified glucose biosensor exhibits a limit of detection (LOD) of (50 ± 10) µM and also excludes interfering species, such as ascorbic acid, uric acid, and cholesterol, which makes this sensor suitable for glucose determination in real samples. This sensor displays an acceptable reproducibility and stability over time. The current response was maintained over 95% of the initial value after 17 days, and the current difference measurement obtained using different electrodes provided a relative standard deviation (RSD) of 4.47%.

Indexed as

Biosensing TechniquesCelluloseDrug SynergismElectrodesEnzymes, ImmobilizedGlucoseGlucose OxidaseLimit of DetectionNanocompositesNanoparticlesPolymersPyrrolesCelluloseEnzymes, ImmobilizedGlucoseGlucose OxidasePolymerspolypyrrolePyrrolescellulose nanocrystalschemical polymerizationdirect electrochemistryglucose biosensorGOxPPy-CNC nanocomposite

Identifiers

PMID26404269
PMCPMC4634436
OpenAlexW2108849216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.