ArticleJournal of gynecologic oncology2015
Longer waiting times for early stage cervical cancer patients undergoing radical hysterectomy are associated with diminished long-term overall survival.
Article in Journal of gynecologic oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Impact of the diagnosis-surgery interval on survival outcomes and development of a nomogram for predicting survival in early-stage cervical cancer: a Surveillance, Epidemiology, and End Results database analysis.Journal of gynecologic oncology · 2026Article
- Pace of Cervical Cancer Stage Progression Prior to Radiation Therapy Initiation, an Instrumental Variable Analysis.International journal of radiation oncology, biology, physics · 2026Article
- A nomogram-based prediction model for assessing the risk of vain and stump cancer recurrence following radical surgery for cervical cancer.Discover oncology · 2026Article
- Impact of Prolonged Surgical Waiting Time on 5-Year Progression-Free Survival in Patients With Endometrial Cancer.The journal of obstetrics and gynaecology research · 2026Article
- Article
- A NLP-based semi-automatic identification system for delays in follow-up examinations: an Italian case study on clinical referrals.BMC medical informatics and decision making · 2024Article
- Primary care practitioners' priorities for improving the timeliness of cancer diagnosis in primary care: a European cluster-based analysis.BMC health services research · 2023Article
- Article
- Effect of Waiting Time from Pathological Diagnosis to Definitive Concurrent Chemoradiation for Cervical Cancer on Overall Survival.Cancer research and treatment · 2022Article
- Fertility-Sparing Treatment for Young Patients with Early-Stage Cervical Cancer: A Dawn of a New Era.Frontiers in surgery · 2022Article
- Prognosis of Early Stage Cervical Cancer According to Patterns of Recurrence.Cancer management and research · 2021Article
- Wait-time for hysterectomy and survival of women with early-stage cervical cancer: A clinical implication during the coronavirus pandemic.Gynecologic oncology · 2020Observational
- Association of MRI-derived radiomic biomarker with disease-free survival in patients with early-stage cervical cancer.Theranostics · 2020Article
- How European primary care practitioners think the timeliness of cancer diagnosis can be improved: a thematic analysis.BMJ open · 2019Article
- Creating a low-cost virtual reality surgical simulation to increase surgical oncology capacity and capability.Ecancermedicalscience · 2019Article
- Demographic disparities in delay of definitive chemoradiation for anal squamous cell carcinoma: a nationwide analysis.Journal of gastrointestinal oncology · 2018Article
- Article
- HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-β/smad signaling pathway in cervical carcinoma cells.Cancer cell international · 2018Article
- Monocytosis as a prognostic factor for survival in stage IB and IIA cervical cancer.Journal of Cancer · 2018Article
- Impact of time interval between radical hysterectomy with pelvic node dissection and initial adjuvant therapy on oncological outcomes of early stage cervical cancer.Journal of gynecologic oncology · 2017Article
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Abstract
objectiveThe aim of this study was to evaluate the impact of surgical waiting time on clinical outcome in early stage cervical cancer.
methodsThe cohort consisted of 441 patients diagnosed with stages IA2-IB1cervical cancer who underwent radical hysterectomy and pelvic node dissection. The patients were divided into two groups based on surgical waiting time. The associations between waiting time and other potential prognostic factors with clinical outcome were evaluated.
resultsThe median surgical waiting time was 43 days. Deep stromal invasion (hazard ratio [HR], 2.5; 95% confidence interval [CI], 1.4 to 4.6; p=0.003) and lymph node metastasis (HR, 2.9; 95% CI, 1.3 to 6.7; p=0.026) were identified as independent prognostic factors for recurrence-free survival while no prognostic significance of surgical waiting time was found (p=0.677). On multivariate analysis of overall survival (OS), only deep stromal invasion (HR, 2.6; 95% CI, 1.3 to 5.0; p=0.009) and lymph node metastasis (HR, 3.6; 95% CI, 1.5 to 8.6; p=0.009) were identified as independent prognostic factors for OS. Although OS showed no significant difference between short (≤ 8 weeks) and long (>8 weeks) waiting times, multivariate analysis of OS with time-varying effects revealed that a waiting time longer than 8 weeks was associated with poorer long-term survival (after 5 years; HR, 3.4; 95% CI, 1.3 to 9.2; p=0.021).
conclusionA longer surgical waiting time was associated with diminished long-term OS of early stage cervical cancer patients.
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