Evidence map›Paper›PMID 26403844›Full record

ReviewCurrent environmental health reports2015

Maternal Exposure to Synthetic Chemicals and Obesity in the Offspring: Recent Findings.

Yun Liu, Karen E Peterson

Abstract readReview
In one paragraph

Review in Current environmental health reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Prenatal exposure to persistent organic pollutants and childhood obesity: A systematic review and meta-analysis of human studies.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yun LiuDepartment of Nutritional Sciences, University of Michigan School of Public Health, 1415 Washington Heights, 1-1867, Ann Arbor, MI, 48109-2029, USA. yunliu@umich.edu.
Karen E PetersonDepartment of Nutritional Sciences, University of Michigan School of Public Health, 1415 Washington Heights, 1-1867, Ann Arbor, MI, 48109-2029, USA. karenep@umich.edu.

Funding

Project 3: Developmental Exposures and Diet: Epigenetics of Metabolic SyndromeP01ES022844 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PADMANABHAN, VASANTHA, PETERSON, KAREN EILEEN · 2013 to 2018
$3.9M
Project 1: Prenatal Lead Exposure, Early Childhood Growth, and Sexual MaturationP20ES018171 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PETERSON, KAREN EILEEN · 2010 to 2012
$584k
NIEHS NIH HHS 1P01ES022844-01NIEHS NIH HHS P01 ES022844NIEHS NIH HHS P20 ES018171ORD VA RD-83543601
6 · The paper itself

Abstract

Experimental studies suggest perinatal exposures to synthetic chemicals may be associated with early onset obesity, although this hypothesis has not been extensively examined in humans. This article summarizes the evidence relating maternal perinatal exposure to common persistent organic compounds (polychlorinated biphenyl, dichlorodiphenyldichloroethylene, dichlorodiphenyltrichloroethane, hexachlorobenzene, hexachlorocyclohexane), perfluoroalkyls, perfluorooctane sulfonate, polybrominated diphenyl ethers and tributyltin, and nonpersistent compounds (phthalates, bisphenol A) on child obesity during sensitive developmental periods. Twenty-two epidemiologic studies published from 2011 to 2015 offer inconsistent support for the obesogenic effects of most substances and are limited by relatively small sample sizes and indirect measures of adiposity. The clearest findings suggest an influence of maternal dichlorodiphenyldichloroethylene exposure on offspring overweight and obesity. Recommendations for future epidemiological research include longer follow-up of effects of pre- and postnatal exposures in large samples; utilization of direct measures of adiposity; and consideration of effect modification by sex, birth weight, dietary fat, and maternal weight status.

Indexed as

Prenatal Exposure Delayed EffectsChildEnvironmental PollutantsFemaleHexachlorobenzeneHumansHydrocarbons, ChlorinatedMaternal ExposurePediatric ObesityPregnancyEnvironmental PollutantsHexachlorobenzeneHydrocarbons, ChlorinatedChildEnvironmental obesogenInfant growthMaternal exposureObesityOverweightWeight gain

Identifiers

PMID26403844
PMCPMC5482496

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.