ArticleScientific reports2015
Auxenochlorella protothecoides and Prototheca wickerhamii plastid genome sequences give insight into the origins of non-photosynthetic algae.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 34 citations in OpenAlex.
- Targeted genetic manipulation and yeast-like evolutionary genomics in the green alga Auxenochlorella.The Plant cell · 2025Article
- Targeted genetic manipulation and yeast-like evolutionary genomics in the green algabioRxiv : the preprint server for biology · 2025Article
- Plastomes provide new insights into phylogeny and evolution in Chlorellaceae (Chlorophyta, Trebouxiophyceae).BMC plant biology · 2025Article
- Metabolic Adaptations Determine the Evolutionary Trajectory of TOR Signaling in Diverse Eukaryotes.Biomolecules · 2025Article
- Complete mitochondrial genomes of the Prototheca genus: comparative genomics and evolutionary insights.BMC genomics · 2025Article
- Article
- Reduced plastid genomes of colorless facultative pathogens Prototheca (Chlorophyta) are retained for membrane transport genes.BMC biology · 2024Article
- Phenotypic and molecular characterization of Prototheca wickerhamii from a Brazilian case of human systemic protothecosis.PLoS neglected tropical diseases · 2024Article
- Growth and Cell Size of MicroalgaMicroorganisms · 2024Article
- Estimating peanut and soybean photosynthetic traits using leaf spectral reflectance and advance regression models.Planta · 2022Article
- Comparison ofLife (Basel, Switzerland) · 2022Article
- Genome Sequences of Two Strains ofFrontiers in cellular and infection microbiology · 2022Article
- Review
- A first insight into the genome of Prototheca wickerhamii, a major causative agent of human protothecosis.BMC genomics · 2021Article
- Protothecosis in Dogs and Cats-New Research Directions.Mycopathologia · 2021Review
- Genomic Insights into Plastid Evolution.Genome biology and evolution · 2020Review
- Sequencing and Analysis of the Complete Organellar Genomes ofFrontiers in plant science · 2020Article
- Next-Generation Genome Sequencing ofPlants (Basel, Switzerland) · 2019Article
- Active eukaryotes in drinking water distribution systems of ground and surface waterworks.Microbiome · 2019Article
- Genome sequencing of Prototheca zopfii genotypes 1 and 2 provides evidence of a severe reduction in organellar genomes.Scientific reports · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The forfeiting of photosynthetic capabilities has occurred independently many times throughout eukaryotic evolution. But almost all non-photosynthetic plants and algae still retain a colorless plastid and an associated genome, which performs fundamental processes apart from photosynthesis. Unfortunately, little is known about the forces leading to photosynthetic loss; this is largely because there is a lack of data from transitional species. Here, we compare the plastid genomes of two "transitional" green algae: the photosynthetic, mixotrophic Auxenochlorella protothecoides and the non-photosynthetic, obligate heterotroph Prototheca wickerhamii. Remarkably, the plastid genome of A. protothecoides is only slightly larger than that of P. wickerhamii, making it among the smallest plastid genomes yet observed from photosynthetic green algae. Even more surprising, both algae have almost identical plastid genomic architectures and gene compositions (with the exception of genes involved in photosynthesis), implying that they are closely related. This close relationship was further supported by phylogenetic and substitution rate analyses, which suggest that the lineages giving rise to A. protothecoides and P. wickerhamii diverged from one another around six million years ago.
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