Evidence map›Paper›PMID 26403422›Full record

ArticleBulletin of mathematical biology2015

Dynamics of Multi-stage Infections on Networks.

N Sherborne, K B Blyuss, I Z Kiss

Abstract read
In one paragraph

Article in Bulletin of mathematical biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Pairwise approximation forProceedings. Mathematical, physical, and engineering sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

N SherborneDepartment of Mathematics, University of Sussex, Brighton, BN1 9QH, UK.
K B BlyussDepartment of Mathematics, University of Sussex, Brighton, BN1 9QH, UK. k.blyuss@sussex.ac.uk.
I Z KissDepartment of Mathematics, University of Sussex, Brighton, BN1 9QH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard closure, a number of important characteristics of disease dynamics are derived analytically, including the final size of an epidemic and a threshold for epidemic outbreaks, and it is shown how these quantities depend on disease characteristics, as well as the number of disease stages. Stochastic simulations of dynamics on networks are performed and compared to output of pairwise models for several realistic examples of infectious diseases to illustrate the role played by the number of stages in the disease dynamics. These results show that a higher number of disease stages results in faster epidemic outbreaks with a higher peak prevalence and a larger final size of the epidemic. The agreement between the pairwise and simulation models is excellent in the cases we consider.

Indexed as

Models, BiologicalCommunicable DiseasesComputer SimulationEpidemicsHumansInfluenza, HumanMathematical ConceptsSevere Acute Respiratory SyndromeSmallpoxStochastic ProcessesFinal sizeInfectious periodNetworkPairwise approximation

Identifiers

PMID26403422
PMCPMC4651987

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.