ArticleEye (London, England)2015
Retinal nerve fiber layer thickness in prematurity is correlated with stage of retinopathy of prematurity.
Article in Eye (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Characteristics of optical coherence tomography in patients with iron deficiency anemia : a systematic review and meta-analysis.BMC ophthalmology · 2024Pooled it
- Optic Nerve Alterations Following Intravitreal Injection and Laser in Infants With Retinopathy of Prematurity.Investigative ophthalmology & visual science · 2026Article
- Effect of intravitreal injection on optic nerve in infants with retinopathy of prematurity: a long-term follow-up study.The British journal of ophthalmology · 2025Article
- Imprint of preterm birth with very low birth weight on optic disc OCT in adulthood-A two-country birth cohort study.Acta ophthalmologica · 2025Article
- The impact of perinatal brain injury on retinal nerve fiber layer thickness and optic nerve head parameters of premature children.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Refractive status and retinal morphology in children with a history of intravitreal ranibizumab for retinopathy of prematurity.European journal of pediatrics · 2023Article
- Retinal and peripapillary vascular deformations in prematurely born children aged 4-12 years with a history of retinopathy of prematurity.Scientific reports · 2023Article
- The Relationship Between Fetal Growth and Retinal Nerve Fiber Layer Thickness in a Cohort of Young Adults.Translational vision science & technology · 2022Article
- Neurosensory Alterations in Retinopathy of Prematurity: A Window to Neurological Impairments Associated to Preterm Birth.Biomedicines · 2022Review
- Association Between Retinal Microanatomy in Preterm Infants and 9-Month Visual Acuity.JAMA ophthalmology · 2022Observational
- Development and Validation of a Deep Learning Model to Predict the Occurrence and Severity of Retinopathy of Prematurity.JAMA network open · 2022Article
- A comparison of posterior segment optical coherence tomography findings in full-term and preterm children without retinopathy of prematurity.Indian journal of ophthalmology · 2021Article
- Birth Weight Is a Significant Predictor of Retinal Nerve Fiber Layer Thickness at 36 Weeks Postmenstrual Age in Preterm Infants.American journal of ophthalmology · 2021Observational
- Association of Birth Weight with Peripapillary Retinal Nerve Fiber Layer Thickness in Adulthood-Results from a Population-Based Study.Investigative ophthalmology & visual science · 2020Article
- The inner retinal structures of the eyes of children with a history of retinopathy of prematurity.Eye (London, England) · 2018Article
- The range of peripapillary retinal nerve fibre layer and optic disc parameters, in children aged up to but not including 18 years of age who were born prematurely: protocol for a systematic review.Systematic reviews · 2016Article
- Optical coherence tomography of the preterm eye: from retinopathy of prematurity to brain development.Eye and brain · 2016Review
- Peripapillary Retinal Nerve Fiber Layer Thickness Changes in Preterm Children with or without Retinopathy of Prematurity History.Journal of current ophthalmologyArticle
- Swept-source optical coherence tomography findings in premature children with a history of retinopathy of prematurity at 5 years of age.Arquivos brasileiros de oftalmologiaArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare retinal nerve fiber layer (RNFL) thickness profiles between preterm and full-term children and to investigate factors affecting the RNFL distribution in preterm children.
methodsWe performed Spectral domain optical coherence tomography (SD-OCT) peripapillary RNFL circular scan centered on the optic disc in 50 premature and 58 full-term children. RNFL thickness profiles were compared between preterm and full-term children using a linear regression model. Among preterm patients in this study, 20 patients previously received laser treatment for severe retinopathy of prematurity (ROP).
resultsGlobal average, nasal, and superior disc RNFL thickness profiles were significantly smaller in preterm children (92.70±16.57 μm, 56.02±17.04 μm, and 108.74±27.36 μm, respectively) compared with full-term children (101.63±9.21 μm, P=0.006, 69.14±14.15 μm, P<0.001, and superior, 129.11±18.14 μm, P<0.001, respectively). Multivariable analysis revealed that ROP stage was inversely correlated with nasal RNFL thickness (P=0.010).
conclusionsOur SD-OCT data demonstrate decreased global average, nasal, and superior disc RNFL thicknesses in preterm children. ROP stage was inversely correlated with nasal RNFL thickness. Further studies are needed to better understand the association between these structural changes and visual functions in preterm children.
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