ArticleGenome biology2015
Metassembler: merging and optimizing de novo genome assemblies.
Article in Genome biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
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Who cites it
76 citing papers in PubMed.
- Article
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- Diversity of lncRNAs in the pan-transcriptome of maize inbred lines.BMC genomics · 2026Article
- JG2: an updated version of the Japanese population-specific reference genome.Human genome variation · 2025Article
- Autocycler: long-read consensus assembly for bacterial genomes.Bioinformatics (Oxford, England) · 2025Article
- The Vulpes vulpes montana genome provides insights into high-altitude adaptation mechanisms of the Vulpes species.Communications biology · 2025Article
- Physiology, Heavy Metal Resistance, and Genome Analysis of TwoMicroorganisms · 2025Article
- Decontamination of DNA sequences from a Streptomyces genome for optimal genome mining.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Amphibian skin bacteria contain a wide repertoire of genes linked to their antifungal capacities.World journal of microbiology & biotechnology · 2025Article
- Article
- Genome sequence of the Mediterranean red coral Corallium rubrum.BMC research notes · 2024Article
- Tracking antimicrobial resistance transmission in urban and rural communities in Bangladesh: a One Health study of genomic diversity of ESBL-producing and carbapenem-resistantMicrobiology spectrum · 2024Article
- A New Species ofInsects · 2024Article
- Draft genomes of fourMicrobiology resource announcements · 2024Article
- Genome sequence of anMicrobiology resource announcements · 2024Article
- Article
- High quality genome assembly of the anhydrobiotic midge provides insights on a single chromosome-based emergence of extreme desiccation tolerance.NAR genomics and bioinformatics · 2022Article
- Article
- Assemblies of the genomes of parasitic wasps using meta-assembly and scaffolding with genetic linkage.G3 (Bethesda, Md.) · 2022Article
- Comparative analysis of draft genome assemblies developed from whole genome sequences of twoBiotechnology reports (Amsterdam, Netherlands) · 2021Article
16 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
Abstract
Genome assembly projects typically run multiple algorithms in an attempt to find the single best assembly, although those assemblies often have complementary, if untapped, strengths and weaknesses. We present our metassembler algorithm that merges multiple assemblies of a genome into a single superior sequence. We apply it to the four genomes from the Assemblathon competitions and show it consistently and substantially improves the contiguity and quality of each assembly. We also develop guidelines for meta-assembly by systematically evaluating 120 permutations of merging the top 5 assemblies of the first Assemblathon competition. The software is open-source at http://metassembler.sourceforge.net .
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