Evidence map›Paper›PMID 26403144›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Relationships between left ventricular asynchrony and myocardial blood flow.

Andrew Van Tosh, John R Votaw, C David Cooke, Nathaniel Reichek, Christopher J Palestro, Kenneth J Nichols

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Left ventricular regional asynchrony: Earliest marker for ischemic cardiomyopathy?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  2. Early onset of left ventricular regional asynchrony in arteries with sub-clinical stenosis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  3. Prolonged left ventricular dysfunction following pharmacologic stress myocardial perfusion imaging: Should we be less stunned than in the past?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  4. Article
  5. Ventricular synchrony is not significantly determined by absolute myocardial perfusion in patients with chronic heart failure: AJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  6. Dyssynchrony as a marker of adverse prognosis among patients with coronary artery disease and heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  7. Phase analysis of gated PET in the evaluation of mechanical ventricular synchrony: A narrative overview.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Review
  8. Review
  9. Review
  10. Vasodilator stress and left ventricular asynchrony.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Andrew Van ToshResearch Department, St. Francis Hospital, Roslyn, NY, USA. Andrew.Vantosh@chsli.org.
John R VotawDepartment of Radiology, Emory University, Atlanta, GA, USA.
C David CookeDepartment of Radiology, Emory University, Atlanta, GA, USA.
Nathaniel ReichekResearch Department, St. Francis Hospital, Roslyn, NY, USA.
Christopher J PalestroDivision of Nuclear Medicine and Molecular Imaging, North Shore - Long Island Jewish Health System, Manhasset & New Hyde Park, NY, USA.
Kenneth J NicholsDivision of Nuclear Medicine and Molecular Imaging, North Shore - Long Island Jewish Health System, Manhasset & New Hyde Park, NY, USA.

Funding

3D Fusion and Visualization of Quantified Cardiac CTCA and Nuclear Perfusion ImagR01HL085417 · NHLBI · EMORY UNIVERSITY · PI GARCIA, ERNEST V · 2008 to 2011
$1.9M
NHLBI NIH HHS R01 HL085417
6 · The paper itself

Abstract

objective

methodsWe retrospectively analyzed

resultsAmong the 195 patients, 64 had LVAS at rest, of whom 13 reverted to normal and 51 continued to have LVAS with stress. Patients who did not improve had lower stress MBF (1.04 ± 0.69 vs 1.58 ± 0.67, p = .02) and coronary flow reserve (1.94 ± 1.16 vs 3.04 ± 1.22, p = .01) than those who did improve. ROC analysis indicated that the parameter most strongly associated with improvement in asynchrony for patients with resting LVAS was reduction in MBF heterogeneity (ROC area (accuracy) = 84%, sensitivity = 92%, and specificity = 67%).

conclusionLVAS is highly correlated with MBF and CVR, with stress-induced improvement in synchronicity most strongly associated with improved MBF homogeneity.

Indexed as

Blood Flow VelocityCoronary CirculationMyocardial ContractionAgedCoronary Artery DiseaseExercise TestFemaleHumansMaleMyocardial Perfusion ImagingPositron-Emission TomographyRadiopharmaceuticalsReproducibility of ResultsRubidiumSensitivity and SpecificityStroke VolumeRadiopharmaceuticalsRubidiumasynchronycoronary flow reservePET/CTrubidium isotopes

Identifiers

PMID26403144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.