ReviewNutrients2015
Regulation of Dendritic Cell Function by Vitamin D.
Review in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04308161 (The Effectiveness of Topical Oral Vitamin D Gel in Prevention of Radiation-induced Oral Mucositis), which is not on this map. Cited by 115 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effectiveness of Topical Oral Vitamin D Gel in Prevention of Radiation-induced Oral Mucositis
Who cites it
115 citing papers in PubMed, 5 syntheses or guidelines pooled it, 216 citations in OpenAlex.
- The role of vitamin D in diabetic foot ulcer; an umbrella review of meta-analyses.Frontiers in nutrition · 2024Pooled it
- The Role of Vitamin D Supplementation on Airway Remodeling in Asthma: A Systematic Review.Nutrients · 2023Pooled it
- A Meta-Analysis on Vitamin D Supplementation and Asthma Treatment.Frontiers in nutrition · 2022Pooled it
- The Health Effects of Vitamin D and Probiotic Co-Supplementation: A Systematic Review of Randomized Controlled Trials.Nutrients · 2020Pooled it
- The association between vitamin D and COPD risk, severity, and exacerbation: an updated systematic review and meta-analysis.International journal of chronic obstructive pulmonary disease · 2016Pooled it
- Serum 25-Hydroxyvitamin D Status Across Vertebrate Species: A Comparative Review.International journal of molecular sciences · 2026Review
- Effect of Vitamin D Supplementation on Total Knee Arthroplasty Outcomes: A Systematic Review.Orthopaedic journal of sports medicine · 2026Review
- Is Obesity a Modifiable Risk Factor in Multiple Sclerosis? Mechanistic Insights into Neuroinflammation and Oxidative Damage.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026Review
- Vitamin D Supplementation Improves Serological Parameters and Recovery Outcomes in COVID-19 Patients.Endocrine, metabolic & immune disorders drug targets · 2026Observational
- Gut microbiota interactions with the immunomodulatory role of 25-hydroxyvitamin D in children with infectious mononucleosis.Frontiers in medicine · 2026Article
- Modulation of Peripheral Immune Cells Following Vitamin DNutrients · 2025Article
- The gut-skin axis: a bi-directional, microbiota-driven relationship with therapeutic potential.Gut microbes · 2025Review
- Vitamin D and the aging skin: insights into oxidative stress, inflammation, and barrier function.Immunity & ageing : I & A · 2025Review
- The Role of Vitamin D and Vitamin D Receptor in Sepsis.Current issues in molecular biology · 2025Review
- Review
- Optimizing serum 25(OH)D levels to mitigate the risk of age-related ocular diseases: insights from a large-scale prospective cohort study.Nutrition journal · 2025Article
- Molecular Insight into the Role of Vitamin D in Immune-Mediated Inflammatory Diseases.International journal of molecular sciences · 2025Review
- Genetic Polymorphisms in Cytochrome P450 Enzymes Involved in Vitamin D Metabolism and the Vitamin D Receptor: Their Clinical Relevance.Journal of personalized medicine · 2025Review
- Association of Vitamin D Status with Immune Markers in a Cohort of Healthy Adults.The Journal of nutrition · 2025Article
- Persistent symptoms in euthyroid Hashimoto's thyroiditis: current hypotheses and emerging management strategies.Frontiers in endocrinology · 2025Review
55 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Studies over the last two decades have revealed profound immunomodulatory aspects of vitamin D on various aspects of the immune system. This review will provide an overview of Vitamin D metabolism, a description of dendritic cell subsets, and highlight recent advances on the effects of vitamin D on dendritic cell function, maturation, cytokine production and antigen presentation. The active form of vitamin D, 1,25(OH)₂D₃, has important immunoregulatory and anti-inflammatory effects. Specifically, the 1,25(OH)₂D₃-Vitamin D₃ complex can affect the maturation and migration of many dendritic cell subsets, conferring a special immunoregulatory role as well as tolerogenic properties affecting cytokine and chemokine production. Furthermore, there have been many recent studies demonstrating the effects of Vitamin D on allergic disease and autoimmunity. A clear understanding of the effects of the various forms of Vitamin D will provide new opportunities to improve human health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.