ArticlePharmaceuticals (Basel, Switzerland)2015
Pharmacogenomics Implications of Using Herbal Medicinal Plants on African Populations in Health Transition.
Article in Pharmaceuticals (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Pharmacokinetics of Sulfadoxine and Pyrimethamine for Intermittent Preventive Treatment of Malaria During Pregnancy and After Delivery.CPT: pharmacometrics & systems pharmacology · 2017Trial
- Safety of herbal medicine in the postpartum period: A hospital-based single-arm, prospective observational study (SAFEHERE-PC).Integrative medicine research · 2026Article
- Herbal product use in urban slum communities of Freetown, Sierra Leone: Consumption patterns, predictors, and ethnomedicinal applications.Journal of ethnobiology and ethnomedicine · 2026Article
- Virtual Screening of Phytochemicals From Medicinal Plants as Promising PDE5 Inhibitors Against Erectile Dysfunction.Food science & nutrition · 2026Article
- Special Issue: "Therapeutic Potential of Natural Compounds: Insights into Mechanisms, Molecular Docking, and Biological Activities".International journal of molecular sciences · 2025Article
- Evaluation of antibacterial and antidiarrheal properties of3 Biotech · 2025Article
- The role of microalgal extracts and their combination with tamoxifen in the modulation of breast cancer immunotherapy (Review).Molecular and clinical oncology · 2025Review
- Therapeutic Effects of Natural Products on Human Diseases.Life (Basel, Switzerland) · 2024Article
- Article
- The Main Medicinal Plants in Arid Regions of Uzbekistan and Their Traditional Use in Folk Medicine.Plants (Basel, Switzerland) · 2023Article
- Phytochemical and Biological Investigation of an Indigenous Plant of Bangladesh,Molecules (Basel, Switzerland) · 2023Article
- Anti-human immunodeficiency virus-1 activity of MoMo30 protein isolated from the traditional African medicinal plant Momordica balsamina.Virology journal · 2023Article
- Pharmacogenomics of Hypertension in Africa: Paving the Way for a Pharmacogenetic-Based Approach for the Treatment of Hypertension in Africans.International journal of hypertension · 2023Review
- Warfarin Pharmacogenomics for Precision Medicine in Real-Life Clinical Practice in Southern Africa: Harnessing 73 Variants in 29 Pharmacogenes.Omics : a journal of integrative biology · 2022Article
- Cytochrome P450 Enzyme Inhibition and Herb-Drug Interaction Potential of Medicinal Plant Extracts Used for Management of Diabetes in Nigeria.European journal of drug metabolism and pharmacokinetics · 2021Article
- Potential challenges to sustained viral load suppression in the HIV treatment programme in South Africa: a narrative overview.AIDS research and therapy · 2021Review
- Worldwide Research Trends on Medicinal Plants.International journal of environmental research and public health · 2020Article
- Effects of extracts and molecules derived from medicinal plants of West Africa in the prevention and treatment of gynecological cancers. A Review.American journal of cancer research · 2020Review
- The potential of plant systems to break the HIV-TB link.Plant biotechnology journal · 2019Review
- Herbal remedies used for the treatment of infertility in males and females by traditional healers in the rural areas of the West Bank/Palestine.BMC complementary and alternative medicine · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most accessible points of call for most African populations with respect to primary health care are traditional health systems that include spiritual, religious, and herbal medicine. This review focusses only on the use of herbal medicines. Most African people accept herbal medicines as generally safe with no serious adverse effects. However, the overlap between conventional medicine and herbal medicine is a reality among countries in health systems transition. Patients often simultaneously seek treatment from both conventional and traditional health systems for the same condition. Commonly encountered conditions/diseases include malaria, HIV/AIDS, hypertension, tuberculosis, and bleeding disorders. It is therefore imperative to understand the modes of interaction between different drugs from conventional and traditional health care systems when used in treatment combinations. Both conventional and traditional drug entities are metabolized by the same enzyme systems in the human body, resulting in both pharmacokinetics and pharmacodynamics interactions, whose properties remain unknown/unquantified. Thus, it is important that profiles of interaction between different herbal and conventional medicines be evaluated. This review evaluates herbal and conventional drugs in a few African countries and their potential interaction at the pharmacogenomics level.
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Registered trials
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