ReviewInternational journal of molecular sciences2015
Interaction of DNA with Simple and Mixed Ligand Copper(II) Complexes of 1,10-Phenanthrolines as Studied by DNA-Fiber EPR Spectroscopy.
Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Article
- Heteroleptic Metal Complexes of 4-(2-Pyridylazo)resorcinol and 1,10-Phenanthroline: Synthesis, Comprehensive Characterization, Electrochemical and Antioxidant Properties, and Computational Investigations.Bioinorganic chemistry and applications · 2026Article
- A perception into binary and ternary copper (II) complexes: synthesis, characterization, DFT modeling, antimicrobial activity, protein binding screen, and amino acid interaction.BMC chemistry · 2023Article
- Development of Copper Complexes with Diimines and Dipicolinate as Anticancer Cytotoxic Agents.Pharmaceutics · 2023Article
- New Copper(II)-L-Dipeptide-Bathophenanthroline Complexes as Potential Anticancer Agents-Synthesis, Characterization and Cytotoxicity Studies-And Comparative DNA-Binding Study of Related Phen Complexes.Molecules (Basel, Switzerland) · 2023Article
- Mapping the DNA Damaging Effects of Polypyridyl Copper Complexes with DNA Electrochemical Biosensors.Molecules (Basel, Switzerland) · 2022Article
- Antiproliferative and antibacterial properties of biocompatible copper(II) complexes bearing chelating N,N-heterocycle ligands and potential mechanisms of action.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2021Article
- A trade-off for covalent and intercalation binding modes: a case study for Copper (II) ions and singly modified DNA nucleoside.Scientific reports · 2019Article
- Cytotoxic phenanthroline derivatives alter metallostasis and redox homeostasis in neuroblastoma cells.Oncotarget · 2018Article
- Recent Advances in Copper Intercalators as Anticancer Agents.Journal of fluorescence · 2018Review
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
The interaction of simple and ternary Cu(II) complexes of 1,10-phenanthrolines with DNA has been studied extensively because of their various interesting and important functions such as DNA cleavage activity, cytotoxicity towards cancer cells, and DNA based asymmetric catalysis. Such functions are closely related to the DNA binding modes of the complexes such as intercalation, groove binding, and electrostatic surface binding. A variety of spectroscopic methods have been used to study the DNA binding mode of the Cu(II) complexes. Of all these methods, DNA-fiber electron paramagnetic resonance (EPR) spectroscopy affords unique information on the DNA binding structures of the complexes. In this review we summarize the results of our DNA-fiber EPR studies on the DNA binding structure of the complexes and discuss them together with the data accumulated by using other measurements.
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