ArticleThe journal of trauma and acute care surgery2015
Alcohol exposure, injury, and death in trauma patients.
Article in The journal of trauma and acute care surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Moving the needle on minimum standards: alcohol's dose-dependent association with reinjury is worthy of targeted intervention.Trauma surgery & acute care open · 2025Article
- Role of blood alcohol level on the risk and severity of trauma recurrence.Trauma surgery & acute care open · 2025Article
- Alcohol is a risk factor for helmet non-use and fatalities in off-road vehicle and motorcycle crashes.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Forensic medical evaluation of penetrating abdominal injuries.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024Article
- Effect of acute alcohol consumption on blunt bowel mesenteric injury: a retrospective analysis.BMC emergency medicine · 2024Article
- Likelihood of Craniofacial Injury and Hospitalization with Alcohol Use While Skateboarding and Scootering.Craniomaxillofacial trauma & reconstruction · 2023Article
- Trauma center risk conditions for blood alcohol-positive and alcohol misuse patients: a retrospective study.International journal of burns and trauma · 2022Article
- The role of alcohol and other drugs on emergency department traumatic injury mortality in the United States.Drug and alcohol dependence · 2021Article
- Underreporting of alcohol use in trauma patients: A retrospective analysis.Substance abuse · 2021Article
- The influence of alcohol on the outcome of trauma patients: a matched-pair analysis of the TraumaRegister DGUEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020Article
- Blood Alcohol Concentration Is Associated With Improved AIS Motor Score After Spinal Cord Injury.Topics in spinal cord injury rehabilitation · 2020Article
- Natural language processing and machine learning to identify alcohol misuse from the electronic health record in trauma patients: development and internal validation.Journal of the American Medical Informatics Association : JAMIA · 2019Observational
- Use of alcohol biomarkers to identify alcohol misuse in organ donors.Alcohol (Fayetteville, N.Y.) · 2018Article
- Summary of the 2017 Alcohol and Immunology Research Interest Group (AIRIG) meeting.Alcohol (Fayetteville, N.Y.) · 2018Article
- Letter to the Editor: Ding Q, Wang Z, Shen M, Su Z, and Shen L (2017) Acute Alcohol Exposure and Risk of Mortality of Patients with Traumatic Brain Injury: A Systematic Review and Meta-Analysis.Alcoholism, clinical and experimental research · 2017Article
- Cut-Point Levels of Phosphatidylethanol to Identify Alcohol Misuse in a Mixed Cohort Including Critically Ill Patients.Alcoholism, clinical and experimental research · 2017Article
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4 authors.
Funding
Abstract
backgroundThe association of alcohol use with in-hospital trauma deaths remains unclear. This study identifies the association of blood alcohol content (BAC) with in-hospital death accounting for injury severity and mechanism.
methodsThis study involves a historical cohort of 46,222 admissions to a statewide trauma center between January 1, 2002, and October 31, 2011. Blood alcohol was evaluated as an ordinal variable: 1 mg/dL to 100 mg/dL as moderate blood alcohol, 101 mg/dL to 230 mg/dL as high blood alcohol, and greater than 230 mg/dL as very high blood alcohol.
resultsBlood alcohol was recorded in 44,502 patients (96.3%). Moderate blood alcohol was associated with an increased odds for both penetrating mechanism (odds ratio [OR], 2.22; 95% confidence interval [CI], 2.04-2.42) and severe injury (OR, 1.25; 95% CI, 1.16-1.35). Very high blood alcohol had a decreased odds for penetrating mechanism (OR, 0.75; 95% CI, 0.67-0.85) compared with the undetectable blood alcohol group. An inverse U-shaped association was shown for severe injury and penetrating mechanism by alcohol group (p < 0.001). Moderate blood alcohol had an increased odds for in-hospital death (OR, 1.50; 95% CI, 1.25-1.79), and the odds decreased for very high blood alcohol (OR, 0.69; 95% CI, 0.54-0.87). An inverse U-shaped association was also shown for in-hospital death by alcohol group (p < 0.001). Model discrimination for in-hospital death had an area under the receiver operating characteristic curve of 0.64 (95% CI, 0.63-0.65).
conclusionInjury severity and mechanism are strong intermediate outcomes between alcohol and death. Severe injury itself carried the greatest odds for death, and with the moderate BAC group at greatest odds for severe injury and the very high BAC group at the lowest odds for severe injury. The result was a similar inverse-U shaped curve for odds for in-hospital death. Clear associations between blood alcohol and in-hospital death cannot be analyzed without consideration for the different injuries by blood alcohol groups. LEVEL OF EVIDENCE: Epidemiologic study, level III.
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