Evidence map›Paper›PMID 26402414›Full record

ArticleBritish journal of cancer2015

A prospective study of coffee intake and pancreatic cancer: results from the NIH-AARP Diet and Health Study.

K A Guertin, N D Freedman, E Loftfield, R Z Stolzenberg-Solomon, B I Graubard, R Sinha

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Coffee Consumption and Cancer Risk: An Assessment of the Health Implications Based on Recent Knowledge.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2021
    Pooled it
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  5. Review
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  9. Environmental Risk Factors of Pancreatic Cancer.Journal of clinical medicine · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

K A GuertinNutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, 9609 Medical Center Drive, Room 6E326, MSC 9760, Bethesda, MD 20892, USA.
N D FreedmanNutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, 9609 Medical Center Drive, Room 6E326, MSC 9760, Bethesda, MD 20892, USA.
E LoftfieldNutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, 9609 Medical Center Drive, Room 6E326, MSC 9760, Bethesda, MD 20892, USA.
R Z Stolzenberg-SolomonNutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, 9609 Medical Center Drive, Room 6E326, MSC 9760, Bethesda, MD 20892, USA.
B I GraubardBiostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD, USA.
R SinhaNutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, 9609 Medical Center Drive, Room 6E326, MSC 9760, Bethesda, MD 20892, USA.
National Institutes of Health · USNational Cancer Institute · USDepartment of Health and Human Services · US

Funding

Prospective Studies of Diet and Cancer in the AARP CohortZIACP010196 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI SINHA, RASHMI · 2009 to 2025
$21.0M
Intramural NIH HHS
6 · The paper itself

Abstract

backgroundEvidence evaluating the association between type of coffee intake (caffeinated, decaffeinated) and risk of pancreatic cancer is limited.

methodsIn the US NIH-AARP Diet and Health Study, we used Cox proportional hazards regression to estimate hazard ratios and 95% confidence intervals (CIs) for coffee intake and risk of pancreatic cancer among 457 366 US adults.

resultsOver 4 155 256 person-years of follow-up, 1541 incident first primary pancreatic cancers occurred. Following detailed adjustment for tobacco smoking history, risk estimates for coffee drinking were not statistically significant; compared with never drinkers of coffee, the hazard ratios (95% CI) were 1.05 (0.85-1.30), 1.06 (0.86-1.31), 1.03 (0.85-1.25), 1.00 (0.79-1.25), and 1.24 (0.93-1.65) for <1, 1, 2-3, 4-5, and ≥6 cups per day, respectively (P-value for trend 0.46). The observed null association was consistent across all examined strata (sex, smoking status, coffee caffeination, and prevalent diabetes).

conclusionsIn a prospective study of coffee intake with the largest number of pancreatic cancer cases to date, we did not observe an association between total, caffeinated, or decaffeinated coffee intake and pancreatic cancer.

Indexed as

AgedCoffeeFemaleHealth SurveysHumansMaleMiddle AgedPancreatic NeoplasmsProportional Hazards ModelsProspective StudiesRisk AssessmentRisk FactorsSmokingUnited StatesCoffee

Identifiers

PMID26402414
PMCPMC4651134
OpenAlexW2235208106

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.