Evidence map›Paper›PMID 26402396›Full record

ArticlePsychophysiology2015

Longitudinal stability and predictive utility of the visual P3 response in adults with externalizing psychopathology.

Henry H Yoon, Stephen M Malone, William G Iacono

Abstract readTwin Study
In one paragraph

Article in Psychophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. The Startle-Evoked Potential: Negative Affect and Severity of Pathology in Anxiety/Mood Disorders.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018
    Article
  10. Review
  11. Article
  12. Endophenotype best practices.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2017
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Henry H YoonDepartment of Psychology, Augsburg College, Minneapolis, Minnesota, USA.
Stephen M MaloneDepartment of Psychology, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA.
William G IaconoDepartment of Psychology, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA.

Funding

Twin Family Study of Vulnerability to Substance AbuseR37DA005147 · NIDA · UNIVERSITY OF MINNESOTA · PI IACONO, WILLIAM G. · 2009 to 2018
$6.4M
TWIN/FAMILY STUDY OF VULNERABILITY TO SUBSTANCE ABUSER01DA005147 · NIDA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI IACONO, WILLIAM G · 1987 to 2007
$5.5M
Maximum Drinks, Alcoholism and Psychopathology RiskK01AA015621 · NIAAA · UNIVERSITY OF MINNESOTA · PI MALONE, STEPHEN MATTHEW · 2006 to 2010
$362k
NIAAA NIH HHS K01 AA015621NIDA NIH HHS R01 DA005147NIDA NIH HHS R01 DA5147NIDA NIH HHS R37 DA005147
6 · The paper itself

Abstract

We determined whether time-domain P3 amplitude and time-frequency principal component (TF-PC) reductions could serve as stable and predictive developmental endophenotypes of externalizing psychopathology. Participants from the Minnesota Twin Family Study were assessed at age 17 and again at age 29 for lifetime externalizing (EXT) disorders. Comparisons of P3 amplitude and TF-PCs at delta and theta frequencies were made between EXT and unaffected comparison subjects. P3 amplitude and all five extracted TF-PCs were significantly reduced in those presenting lifetime EXT disorders at both ages 17 and 29 and showed substantial 12-year rank-order stability. P3 amplitude and delta TF-PCs measured at age 17 also predicted subsequent development of EXT by age 29, with every 1-microvolt decrease in age 17 amplitude associated with an approximately 5% increase in risk for an EXT diagnosis by age 29. Overall, results from this study further confirm that these P3-derived brain measures maintain their potential as putative EXT endophenotypes through the third decade of life.

Indexed as

AdolescentAdultAntisocial Personality DisorderBrainDiseases in TwinsElectroencephalographyEvent-Related Potentials, P300HumansMaleSubstance-Related DisordersTwinsDevelopmental endophenotypeExternalizing disordersLongitudinalP3 amplitudeSubstance dependenceTime-frequency principal components

Identifiers

PMID26402396
PMCPMC4715720

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.