Trial reportJournal of Alzheimer's disease : JAD2015
Depression and Suicidal Ideation During Two Psychosocial Treatments in Older Adults with Major Depression and Dementia.
Trial report in Journal of Alzheimer's disease : JAD, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis.BMJ (Clinical research ed.) · 2021Pooled it
- Effectiveness of interventions for managing multiple high-burden chronic diseases in older adults: a systematic review and meta-analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2018Pooled it
- Measures used to evaluate psychosocial interventions in dementia care: A narrative review and synthesis.Journal of Alzheimer's disease : JAD · 2026Review
- Brief psychological intervention for suicide prevention based on problem-solving applied in different formats to people over 50 years old: protocol for a randomized controlled trial.BMC psychiatry · 2024Article
- Suicide in late life: A viewpoint.Preventive medicine · 2021Article
- Health, social care and technological interventions to improve functional ability of older adults living at home: An evidence and gap map.Campbell systematic reviews · 2021Article
- Management of Late-Life Depression in the Context of Cognitive Impairment: a Review of the Recent Literature.Current psychiatry reports · 2019Review
- Cognitive Reappraisal Intervention for Suicide Prevention (CRISP) for Middle-Aged and Older Adults Hospitalized for Suicidality.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2018Article
- Refining Suicide Prevention: a Narrative Review on Advances in Psychotherapeutic Tools.Current psychiatry reports · 2018Review
- Psychosocial Suicide Prevention Interventions in the Elderly: A Mini-Review of the Literature.Frontiers in psychology · 2018Review
- Advances in Psychotherapy for Depressed Older Adults.Current psychiatry reports · 2017Review
- Problem Adaptation Therapy for Pain (PATH-Pain): A Psychosocial Intervention for Older Adults with Chronic Pain and Negative Emotions in Primary Care.Geriatrics (Basel, Switzerland) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDepression is prevalent in dementia and contributes to poor outcomes for patients and their families. Antidepressants have limited efficacy in older adults with major depression and dementia, and psychosocial interventions are under-investigated.
objectiveTo examine the course, predictors and moderators of depression and suicidal ideation during 12 weeks of home-delivered Problem Adaptation Therapy (PATH) versus Supportive Therapy for Cognitively Impaired Older Adults (ST-CI) in 39 older adults with major depression and dementia.
methodsThirty-nine older adults with major depression, mild or moderate dementia, and disability participated in a randomized controlled trial that compared the efficacy of PATH versus ST-CI. Depression and suicidal ideation were assessed with Cornell Scale for Depression in Dementia Total Score and Suicide Item.
resultsPATH participants had significantly greater reduction in depression than ST-CI participants over 12 weeks of treatment. PATH participants with high social support had the greatest reduction in depression. Both treatments had comparable reduction in suicidal ideation.
conclusionPATH is more effective in reducing depression in older adults with major depression and dementia compared to ST-CI. These results are clinically significant as antidepressants have limited efficacy in this population. Home-delivered psychosocial treatments may reduce suicidal ideation in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.