Evidence map›Paper›PMID 26401405›Full record

ReviewJournal of intercultural ethnopharmacology

Caffeic acid phenethyl ester as a remedial agent for reproductive functions and oxidative stress-based pathologies of gonads.

Sumeyya Akyol, Ali Akbas, Ilknur Butun, Muhsin Toktas, Huseyin Ozyurt, Semsettin Sahin, Omer Akyol

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of intercultural ethnopharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Cadmium as a male reproductive toxicant and natural and non-natural ways to tackle it: a review.Environmental science and pollution research international · 2024
    Review
  2. Effects of dietary basil (Veterinary and animal science · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sumeyya AkyolDepartments of Medical Biology, Faculty of Turgut Ozal University Medical, Ankara, Turkey ; Department of Biochemistry, Faculty of Gaziosmanpasa University Medical, Tokat, Turkey.
Ali AkbasDepartment of Biochemistry, Faculty of Gaziosmanpasa University Medical, Tokat, Turkey.
Ilknur ButunDepartment of Biochemistry, Faculty of Gaziosmanpasa University Medical, Tokat, Turkey.
Muhsin ToktasDepartment of Anatomy, Faculty of Turgut Ozal University Medical, Ankara, Turkey.
Huseyin OzyurtDepartment of Biochemistry, Faculty of Gaziosmanpasa University Medical, Tokat, Turkey.
Semsettin SahinDepartment of Biochemistry, Faculty of Gaziosmanpasa University Medical, Tokat, Turkey.
Omer AkyolDepartment of Biochemistry, Faculty of Hacettepe University Medical, Ankara, Turkey.
Tokat Gaziosmanpaşa Üniversitesi · TRHacettepe University · TRTurgut Özal University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the studies on the roles of caffeic acid phenethyl ester (CAPE) in several disease models and cell cultures are tremendously growing. It is such a great molecule that was used by ancient times to ameliorate some diseases and nowadays, it is used by modern medicine to test the effectiveness. In this mini-review article, the protection capability of CAPE, as a liposoluble antioxidant and a potent nuclear factor kappa B inhibitor, on oxidative and non-oxidative ovary, and testis damages has been summarized. In view of our laboratory findings/experience and those reported in the hitherto literature, we suggest that CAPE possesses protective effects for pathologies of the reproductive organs induced by untoward effects of harmful molecules such as free oxygen radicals, pesticides, methotrexate, and MK-801 (dizocilpine).

Indexed as

Caffeic acid phenethyl estergonadsovaryoxidative damageprotectiontestis

Identifiers

PMID26401405
PMCPMC4566781
OpenAlexW2085144808

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.