Evidence map›Paper›PMID 26401272›Full record

ArticleJournal of global health2016

Setting research priorities to improve global newborn health and prevent stillbirths by 2025.

Sachiyo Yoshida, José Martines, Joy E Lawn, Stephen Wall, Joăo Paulo Souza, Igor Rudan, Simon Cousens, neonatal health research priority setting group, Peter Aaby, Ishag Adam and 88 more

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In one paragraph

Article in Journal of global health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. A model for global health education through the Ethiopian newborn quality improvement ECHO initiative.Journal of perinatology : official journal of the California Perinatal Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

98 authors.

Sachiyo YoshidaDepartment of Maternal, Newborn, Child and Adolescent Health, World Health Organization, Geneva, Switzerland.
José MartinesCentre for Intervention Science in Maternal and Child Health, Centre for International Health, University of Bergen, Norway.
Joy E LawnLondon School of Hygiene and Tropical Medicine, London, UK ; Saving Newborn Lives, Save the Children, Washington, USA.
Stephen WallSaving Newborn Lives, Save the Children, Washington, USA.
Joăo Paulo SouzaDepartment of Social Medicine, Ribeirăo Preto School of Medicine, University of Săo Paulo, Brazil.
Igor RudanCentre for Population Health Sciences and Global Health Academy, The University of Edinburgh Medical School, Scotland, UK.
Simon CousensLondon School of Hygiene and Tropical Medicine, London, UK.
neonatal health research priority setting group
Peter AabyBandim Health Project, Indepth Network, Guinea-Bissau.
Ishag AdamFaculty of Medicine, University of Khartoum, Sudan.
Ramesh Kant AdhikariKathmandu Medical College, Nepal.
Namasivayam AmbalavananDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA.
Shams Ei ArifeenCentre for Child and Adolescent Health, International Centre for Diarrhoeal Disease Research, Bangladesh.
Dhana Raj AryalDepartment of Neonatology Paropakar Maternity and women's Hospital, Nepal.
Sk AsiruddinTRAction Bangladesh Project, University Research Co., LLC.
Abdullah BaquiJohns Hopkins Bloomberg School of Public Health, USA.
Aluisio Jd BarrosCentro de Pesquisas Epidemiológicas, Universidade Federal de Pelotas, Brazil.
Christine S BennResearch Center for Vitamins and Vaccines, Statens Serum Institut, and University of Southern Denmark/Odense University Hospital, Denmark.
Vineet BhandariProgram in Perinatal Research, Yale University School of Medicine, USA.
Shinjini BhatnagarPediatric Biology Centre, Translational Health Science and Technology Institute, India.
Sohinee BhattacharyaUniversity of Aberdeen, UK.
Zulfiqar A BhuttaCenter of Excellence in Women and Child Health, the Aga Khan University, Karachi, Pakistan.
Robert E BlackInstitute of International Programs, Johns Hopkins Bloomberg School of Public Health, USA.
Hannah BlencoweThe London School of Hygiene & Tropical Medicine, UK.
Carl BoseThe University of North Carolina at Chapel Hill School of Medicine, USA.
Justin BrownThrasher Research Fund, USA.
Christoph BührerDepartment of Neonatology, Charité University Medical Center, Germany.
Wally CarloUniversity of Alabama at Birmingham, USA.
Jose Guilherme CecattiDepartment of Obstetrics and Gynaecology, School of Medical Sciences, University of Campinas, Brazil.
Po-Yin CheungDepartments of Pediatrics, Pharmacology & Surgery, University of Alberta, Canada.
Robert ClarkCharities, USA.
Tim ColbournUniversity College London Institute for Global Health, UK.
Agustin Conde-AgudeloPerinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development/National Institutes of Health/Department of Health and Human Services, Bethesda, Maryland and Detroit, Michigan, USA.
Erica CorbettIndependent consultant maternal health research, Rwanda.
Andrew E CzeizelFoundation for the Community Control of Hereditary Diseases, Hungary.
Abhik DasBiostatistics and Epidemiology, RTI International, USA.
Louise Tina DayLAMB Integrated Rural Health & Development, Bangladesh.
Carolyn DealDivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases National Institute of Health, USA.
Ashok DeorariAll India Institute of Medical Sciences, India.
Uğur DilmenPediatrics and Neonatology, Yıldırım Beyazıt University Medical Faculty, Turkey.
Mike EnglishNuffield Department of Medicine & Department of Paediatrics, University of Oxford, UK and KEMRi-Wellcome Trust Research Programme, Nairobi, Kenya.
Cyril EngmannNewborn Health, Family Health Division, The Bill & Melinda Gates Foundation and the University of North Carolina Schools of Medicine and Public Health, USA.
Fabian EsamaiMoi University, School of Medicine, Kenya.
Caroline FallInternational Paediatric Epidemiology; Affiliations: Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, UK.
Donna M FerrieroDepartment of Pediatrics, UCSF Benioff Children's Hospital, USA.
Peter GisoreSchool of Medicine, Child Health and Pediatrics, Moi University, Kenya.
Tabish HazirChildren's Hospital, Pakistan Institute of Medical Sciences, Pakistan.
Rosemary D HigginsEunice Kennedy Shriver NICHD Neonatal Research Network, Pregnancy and Perinatology, Branch, National Institute of Health, USA.
Caroline Se HomerCentre for Midwifery, Child and Family Health, University of Technology, Sydney, Australia.
D E HoqueCentre for Child and Adolescent Health, International Centre for Diarrhoeal Disease Research, Bangladesh.
Lorentz IrgensUniversity of Bergen and Norwegian Institute of Public Health, Norway.
M T IslamJapan International Cooperation Agency (JICA), Bangladesh.
Joseph de Graft-JohnsonSave the Children, USA.
Martias Alice JoshuaZomba Central Hospital, Ministry of Health, Malawi.
William KeenanSaint Louis University, USA.
Soofia KhatoonPaediatrics and Head of Department Shaheed Suhrawardy Medical College, Bangladesh.
Helle KielerCentre for Pharmacoepidemiology, Karolinska Institute, Sweden.
Michael S KramerDepartments of Pediatrics and of Epidemiology, Biostatistics and Occupational Health, McGill University Faculty of Medicine, Montreal, Quebec, Canada.
Eve M LackritzGlobal Alliance to Prevent Prematurity and Stillbirth (GAPPS), USA.
Tina LavenderUniversity of Manchester School of Nursing Midwifery & Social Work, University of Manchester, UK.
Laurensia LawintonoIndonesian Midwives Association, Indonesia.
Richard LuhangaSave the Children, Malawi.
David MarshSave the Children, USA.
Douglas McMillanDepartment of Paediatrics, Dalhousie University, Canada.
Patrick J McNamaraDepartments of Paediatrics & Physiology, University of Toronto; Physiology & Experimental Medicine program, Hospital for Sick Children, Toronto, Canada.
Ben Willem J MolDepartment of Obstetrics and Gynaecology, Academic Medical Centre Amsterdam, the Netherlands.
Elizabeth MolyneuxPaediatrics and Child Health, College of Medicine Malawi.
G K MukasaInternational Baby Food Action Network, Uganda.
Miriam MutabaziSTRIDES for Family Health, Management Sciences for Health, Uganda.
Luis Carlos NaculFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK.
Margaret NakakeetoKampala Children's Hospital Limited and Childhealth Advocacy International, Uganda.
Indira NarayananUnited States Agency for International Development /Maternal and Child Health Integrated Program, USA.
Bolajoko OlusanyaCentre for Healthy Start Initiative, Nigeria.
David OsrinWellcome Trust Senior Research Fellow in Clinical Science, Institute for Global Health, University College London, UK.
Vinod PaulAll India Institute of Medical Sciences, India.
Christian PoetsUniversity of Tubingen, Germany.
Uma M ReddyEunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, USA.
Mathuram SantoshamCenter for American Indian Health, Johns Hopkins Bloomberg School of Public Health, USA.
Rubayet SayedSave the Children, Bangladesh.
Natalia E Schlabritz-LoutsevitchDepartment of Obstetrics and Gynecology, University of Tennessee Health Science Center, USA.
Nalini SinghalUniversity of Calgary, Canada.
Mary Alice SmithEnvironmental Health Science Department, University of Georgia, USA.
Peter G SmithTropical Epidemiology Group, London School of Hygiene & Tropical Medicine, London, UK.
Sajid SoofiDepartment of Pediatrics & Child Health, Women & Child Health Division, Aga Khan University, Pakistan.
Catherine Y SpongEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, USA.
Shahin SultanaNational Institute of Population Research and Training (NIPORT), Ministry of Health and Family Welfare, Bangladesh.
Antoinette TshefuKinshasa School of Public Health, School of Medicine, University of Kinshasa, Democratic Republic of Congo.
Frank van BelDepartment of Neonatology, University of Utrecht, the Netherlands.
Lauren Vestewig GrayInstitute for Global Health Technologies Rice University, USA.
Peter WaiswaDivision of Global Health, Karolinska Institutet, Sweden.
Wei WangSchool of Medical Sciences, Edith Cowan University, Australia and School of Public Health, Capital Medical University, China.
Sarah LA WilliamsSave the Children UK.
Linda WrightEunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, USA.
Anita ZaidiAga Khan University, Pakistan.
Yanfeng ZhangDepartment of Integrated Early Childhood Development, Capital Institute of Paediatrics, China.
Nanbert ZhongDevelopmental Genetics Laboratory, New York State Institute for Basic Research in Developmental Disabilities, USA.
Isabel ZunigaMédecins sans Frontičres, Belgium.
Rajiv BahlDepartment of Maternal, Newborn, Child and Adolescent Health, World Health Organization, Geneva, Switzerland.

Funding

Medical Research Council MR/K012126/1Wellcome Trust 091561World Health Organization 001
6 · The paper itself

Abstract

backgroundIn 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013-2025.

methodsWe used adapted Child Health and Nutrition Research Initiative (CHNRI) methods for this prioritization exercise. We identified and approached the 200 most productive researchers and 400 program experts, and 132 of them submitted research questions online. These were collated into a set of 205 research questions, sent for scoring to the 600 identified experts, and were assessed and scored by 91 experts.

resultsNine out of top ten identified priorities were in the domain of research on improving delivery of known interventions, with simplified neonatal resuscitation program and clinical algorithms and improved skills of community health workers leading the list. The top 10 priorities in the domain of development were led by ideas on improved Kangaroo Mother Care at community level, how to improve the accuracy of diagnosis by community health workers, and perinatal audits. The 10 leading priorities for discovery research focused on stable surfactant with novel modes of administration for preterm babies, ability to diagnose fetal distress and novel tocolytic agents to delay or stop preterm labour.

conclusionThese findings will assist both donors and researchers in supporting and conducting research to close the knowledge gaps for reducing neonatal mortality, morbidity and long term impairment. WHO, SNL and other partners will work to generate interest among key national stakeholders, governments, NGOs, and research institutes in these priorities, while encouraging research funders to support them. We will track research funding, relevant requests for proposals and trial registers to monitor if the priorities identified by this exercise are being addressed.

Identifiers

PMID26401272
PMCPMC4576458

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.