Evidence map›Paper›PMID 26401223›Full record

ArticleThe Pan African medical journal2015

Prevalence and risk factors for Active Convulsive Epilepsy in Kintampo, Ghana.

Kenneth Ayuurebobi Ae-Ngibise, Bright Akpalu, Anthony Ngugi, Albert Akpalu, Francis Agbokey, Patrick Adjei, Damien Punguyire, Christian Bottomley, Charles Newton, Seth Owusu-Agyei

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in The Pan African medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.

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  15. Prevalence of Epilepsy, Human Cysticercosis, and Porcine Cysticercosis in Western Kenya.The American journal of tropical medicine and hygiene · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Kenneth Ayuurebobi Ae-NgibiseKintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana ; Studies of the Epidemiology of Epilepsy in Demographic Surveillance Systems (SEEDS)-INDEPTH Network Accra, Ghana.
Bright AkpaluKintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana ; Studies of the Epidemiology of Epilepsy in Demographic Surveillance Systems (SEEDS)-INDEPTH Network Accra, Ghana.
Anthony NgugiStudies of the Epidemiology of Epilepsy in Demographic Surveillance Systems (SEEDS)-INDEPTH Network Accra, Ghana ; KEMRI/Wellcome Trust Research Programme, The Centre of Geographical Medicine Research- Coast, Kilifi, Kenya ; Population Health Sciences/Research Support Unit, Faculty of Health Sciences, Aga Khan University- East Africa, Nairobi, Kenya.
Albert AkpaluDepartment of Medicine, Korle Bu Teaching Hospital, Ghana.
Francis AgbokeyKintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana ; Studies of the Epidemiology of Epilepsy in Demographic Surveillance Systems (SEEDS)-INDEPTH Network Accra, Ghana.
Patrick AdjeiDepartment of Medicine, Korle Bu Teaching Hospital, Ghana.
Damien PunguyireKintampo Municipal Hospital, Ghana Health Service, Ghana.
Christian BottomleyMRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, UK.
Charles NewtonStudies of the Epidemiology of Epilepsy in Demographic Surveillance Systems (SEEDS)-INDEPTH Network Accra, Ghana ; KEMRI/Wellcome Trust Research Programme, The Centre of Geographical Medicine Research- Coast, Kilifi, Kenya ; Department of Psychiatry, University of Oxford, United Kingdom.
Seth Owusu-AgyeiKintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana ; Studies of the Epidemiology of Epilepsy in Demographic Surveillance Systems (SEEDS)-INDEPTH Network Accra, Ghana.
Korle Bu Teaching Hospital · GHAga Khan University · PKLondon School of Hygiene & Tropical Medicine · GBUniversity of Oxford · GB

Funding

Medical Research Council MR/K012126/1Wellcome Trust 083744
6 · The paper itself

Abstract

introductionEpilepsy is common in sub-Saharan Africa, but there is little data in West Africa, to develop public health measures for epilepsy in this region.

methodsWe conducted a three-stage cross-sectional survey to determine the prevalence and risk factors for active convulsive epilepsy (ACE), and estimated the treatment gap in Kintampo situated in the middle of Ghana.

results249 people with ACE were identified in a study population of 113,796 individuals. After adjusting for attrition and the sensitivity of the screening method, the prevalence of ACE was 10.1/1000 (95% Confidence Interval (95% CI) 9.5-10.7). In children aged <18 years, risk factors for ACE were: family history of seizures (OR=3.31; 95% CI: 1.83-5.96), abnormal delivery (OR=2.99; 95% CI: 1.07-8.34), problems after birth (OR=3.51; 95% CI: 1.02-12.06), and exposure to Onchocerca volvulus (OR=2.32; 95% CI: 1.12-4.78). In adults, a family history of seizures (OR=1.83; 95% CI: 1.05-3.20), never attended school (OR=11.68; 95% CI: 4.80-28.40), cassava consumption (OR=3.92; 95% CI: 1.14-13.54), pork consumption (OR=1.68; 95% CI: 1.09-2.58), history of snoring at least 3 nights per week (OR=3.40: 95% CI: 1.56-7.41), exposure to Toxoplasma gondii (OR=1.99; 95% CI: 1.15-3.45) and Onchocerca volvulus (OR=2.09: 95% CI: 1.29-3.40) were significant risk factors for the development of ACE. The self-reported treatment gap was 86.9% (95% CI: 83.5%-90.3%).

conclusionACE is common within the middle belt of Ghana and could be reduced with improved obstetric care and prevention of parasite infestations such as Onchocerca volvulus and Toxoplasma gondii.

Indexed as

Public HealthAdolescentAdultChildChild, PreschoolCross-Sectional StudiesEpilepsyFemaleGhanaHumansInfantInfant, NewbornMaleMiddle AgedParasitic DiseasesPrevalenceActive EpilepsyGhanarisk factorssub-Saharan Africa

Identifiers

PMID26401223
PMCPMC4561141
OpenAlexW345999757

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.