ArticleIranian journal of child neurology2015
Incidence and Risk Factors of Neural Tube Defects in Kashan, Central Iran.
Article in Iranian journal of child neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Prevalence of Gestational Diabetes Mellitus in the Middle East and North Africa, 2000-2019: A Systematic Review, Meta-Analysis, and Meta-Regression.Frontiers in endocrinology · 2021Pooled it
- Maternal Folic Acid Supplementation and Neural Tube Defects in Northeast Iran: Insights for Developing Countries.Pediatric health, medicine and therapeutics · 2026Article
- Spina bifida as a multifactorial birth defect: Risk factors and genetic underpinnings.Pediatric discovery · 2025Review
- Determinants of neural tube defect among newborns admitted to neonatal intensive care units of teaching hospitals in Gedeo Zone and Sidama Region, Southern Ethiopia: a case-control study.BMJ paediatrics open · 2024Article
- Neural tube defects among new borns: a cross-sectional study.Frontiers in pediatrics · 2023Article
- Article
- Neural Tube Defects and Associated Factors among Neonates Admitted to the Neonatal Intensive Care Units in Hiwot Fana Specialized University Hospital, Harar, Ethiopia.Global pediatric health · 2020Article
- Determinants of Neural Tube Defects among Newborns in Amhara Region, Ethiopia: A Case-Control Study.International journal of pediatrics · 2020Article
- Epidemiology and determinant factors of neural tube defect: Narrative review.Surgical neurology international · 2020Review
- Estimated global overweight and obesity burden in pregnant women based on panel data model.PloS one · 2018Article
- Risk factors associated with neural tube defects in infants referred to western Iranian obstetrical centers; 2013-2014.Electronic physician · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveNeural tube defects (NTDs) are the most common congenital defects of central nervous system due to neural tube closure deficit during the third and fourth weeks of gestational age. Our study was performed to detect the incidence and risk factors of NTDs in Kashan, center of Iran. MATERIAL &
methodsThis case-control study was done on all pregnancies with NTD affected neonates (n=91) and 209 pregnancies with normal neonates from February 2007 to December 2012 in three hospitals in Kashan, center of Iran. Annual and the mean incidence of NTDs were calculated. Risk factors including neonatal gender, maternal age, gravidity, maternal abortion history, maternal gestational diabetes (GDM), folic acid use, familial marriage, maternal body mass index (BMI), birth season and family history of NTDs were evaluated by interview with mothers. Univariate and multivariate logistic regression were used to analyze the risk factors.
resultsThe mean incidence of NTDs was 2.33 per 1000 births. The multivariate analysis indicated that maternal history of abortion (OR: 4.9, CI: 1.9-12.8), and maternal obesity (OR: 5.4, CI: 1.3-21.8) were significantly associated with NTDs.
conclusionMaternal history of abortion and BMI were the major risk factors of NTDs.
Indexed as
Identifiers
26401153PMC4577698W1840319780What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.