ArticleWorld journal of gastroenterology2015
Platelet count combined with right liver volume and spleen volume measured by magnetic resonance imaging for identifying cirrhosis and esophageal varices.
Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Management of acute variceal bleeding: updated APASL guidelines.Hepatology international · 2025Guideline
- Fully automated spleen segmentation predicts progression-free survival in HCC patients following transarterial radioembolization.European journal of nuclear medicine and molecular imaging · 2026Article
- Prognostic factors for peritoneovenous shunt placement for refractory ascites in liver cirrhosis.World journal of gastroenterology · 2025Article
- Development of a nomogram model based on spleen volume change to predict high-risk esophageal varices in patients with liver cirrhosis.Frontiers in surgery · 2025Article
- Spleen Volume Dynamics and Survival Outcomes in HCC Patients Undergoing Immune Checkpoint Inhibitors: A Retrospective Analysis.Journal of hepatocellular carcinoma · 2025Article
- The impact of hepatic and splenic volumetric assessment in imaging for chronic liver disease: a narrative review.Insights into imaging · 2024Review
- Article
- CT-scan Based Liver and Spleen Volume Measurement as a Prognostic Indicator for Patients with Cirrhosis.The American journal of the medical sciences · 2021Article
- Association between spleen volume and the post-hepatectomy liver failure and overall survival of patients with hepatocellular carcinoma after resection.European radiology · 2021Article
- Prevalence and Risk Factors of Metabolic Associated Fatty Liver Disease in Xinxiang, China.International journal of environmental research and public health · 2020Article
- Article
- Spleen stiffness and volume help to predict posthepatectomy liver failure in patients with hepatocellular carcinoma.Medicine · 2019Article
- A novel, non-invasive model for diagnosing liver fibrosis stage in patients with hepatocellular carcinoma.Scientific reports · 2018Article
- Spleen and Liver Volumetrics as Surrogate Markers of Hepatic Venous Pressure Gradient in Patients With Noncirrhotic Portal Hypertension.Hepatology communications · 2018Article
- Effect of Partial Splenic Embolization on Immune Environment and Hepatic Function in Cirrhosis Patients With Portal Hypertension.In vivo (Athens, Greece)Article
- Νon-invasive screening for esophageal varices in patients with liver cirrhosis.Annals of gastroenterologyReview
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo determine whether the combination of platelet count (PLT) with spleen volume parameters and right liver volume (RV) measured by magnetic resonance imaging (MRI) could predict the Child-Pugh class of liver cirrhosis and esophageal varices (EV).
methodsTwo hundred and five cirrhotic patients with hepatitis B and 40 healthy volunteers underwent abdominal triphasic-enhancement MRI and laboratory examination of PLT in 10(9)/L. Cirrhotic patients underwent endoscopy for detecting EV. Spleen maximal width (W), thickness (T) and length (L) in mm together with spleen volume (SV) and RV in mm(3) were measured by MRI, and spleen volume index (SI) in mm(3) was obtained by W × T × L. SV/PLT, SI/PLT and RV × PLT/SV (RVPS) were calculated and statistically analyzed to assess cirrhosis and EV.
resultsSV/PLT (r = 0.676) and SI/PLT (r = 0.707) increased, and PLT (r = -0.626) and RVPS (r = -0.802) decreased with the progress of Child-Pugh class (P < 0.001 for all). All parameters could determine the presence of cirrhosis, distinguish between each class of Child-Pugh class, and identify the presence of EV [the areas under the curve (AUCs) = 0.661-0.973]. Among parameters, RVPS could best determine presence and each class of cirrhosis with AUCs of 0.973 and 0.740-0.853, respectively; and SV/PLT could best identify EV with an AUC of 0.782.
conclusionThe combination of PLT with SV and RV could predict Child-Pugh class of liver cirrhosis and identify the presence of esophageal varices.
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