CHALLENGES FOR IMPLEMENTING A PTSD PREVENTIVE GENOMIC SEQUENCING PROGRAM IN THE U.S. MILITARY.

Gabriel Lázaro-Muñoz, Eric T Juengst

Open access · greenAbstract read

In one paragraph

Article in Case Western Reserve journal of international law, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact, top 96% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

Polygenic risk associated with post-traumatic stress disorder onset and severity.Translational psychiatry · 2019
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Gabriel Lázaro-MuñozCenter for Genomics and Society at the University of North Carolina School of Medicine. He received his Ph.D. in Neuroscience from New York University, his J.D. and Master of Bioethics from the University of Pennsylvania School of Law and Perelman School of Medicine, and his B.A. from the University of Puerto Rico.

Eric T JuengstUNC Center for Bioethics and Professor in the Department of Social Medicine and the Department of Genetics at the University of North Carolina, Chapel Hill. He received his B.S. in Biology from the University of the South in 1978, and his Ph.D. in Philosophy from Georgetown University in 1985.

University of North Carolina at Chapel Hill · USUniversity of Puerto Rico System · PR

Funding

Center for Genomics and SocietyP50HG004488 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HENDERSON, GAIL E · 2007 to 2017

$12.6M

NHGRI NIH HHS P50 HG004488

6 · The paper itself

Abstract

There is growing interest in using the quickly developing field of genomics to contribute to military readiness and effectiveness. Specifically, influential military advisory panels have recommended that the U.S. military apply genomics to help treat, prevent, or minimize the risk for post-traumatic stress disorder (PTSD) among service members. This article highlights some important scientific, legal, and ethical challenges regarding the development and deployment of a preventive genomic sequencing (PGS) program to predict the risk of PTSD among military service members.

Identifiers

PMID26401056

PMCPMC4577019

OpenAlexW1854428947

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.